用三联抗生素糊剂对未成熟恒牙进行消毒。
Disinfection of immature teeth with a triple antibiotic paste.
作者信息
Windley William, Teixeira Fabricio, Levin Linda, Sigurdsson Asgeir, Trope Martin
机构信息
Department of Endodontics, The University of North Carolina, Chapel Hill, NC 27599, USA.
出版信息
J Endod. 2005 Jun;31(6):439-43. doi: 10.1097/01.don.0000148143.80283.ea.
This study assessed the efficacy of a triple antibiotic paste in the disinfection of immature dog teeth with apical periodontitis. The canals were sampled before (S1) and after (S2) irrigation with 1.25% NaOCL and after dressing with a triple antibiotic paste (S3), consisting of metronidazole, ciprofloxacin, and minocycline. At S1, 100% of the samples cultured positive for bacteria with a mean CFU count of 1.7 x 10. At S2, 10% of the samples cultured bacteria-free with a mean CFU count of 1.4 x 10. At S3, 70% of the samples cultured bacteria-free with a mean CFU count of only 26. Reductions in mean CFU counts between S1 and S2 (p < 0.0001) as well as between S2 and S3 (p < 0.0001) were statistically significant. These results indicate the effectiveness of a triple antibiotic paste in the disinfection of immature teeth with apical periodontitis.
本研究评估了三联抗生素糊剂对患有根尖周炎的未成熟犬牙的消毒效果。在使用1.25%次氯酸钠冲洗前（S1）、冲洗后（S2）以及用由甲硝唑、环丙沙星和米诺环素组成的三联抗生素糊剂换药后（S3）对根管进行取样。在S1时，100%的样本细菌培养呈阳性，平均菌落形成单位（CFU）计数为1.7×10。在S2时，10%的样本培养无菌，平均CFU计数为1.4×10。在S3时，70%的样本培养无菌，平均CFU计数仅为26。S1和S2之间（p<0.0001）以及S2和S3之间（p<0.0001）的平均CFU计数降低具有统计学意义。这些结果表明三联抗生素糊剂对患有根尖周炎的未成熟牙齿消毒有效。
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