• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

1-ethynylpyrene-modified guanine and cytosine as optical labels for DNA hybridization.

作者信息

Wagner Clemens, Rist Manuela, Mayer-Enthart Elke, Wagenknecht Hans-Achim

机构信息

Technical University of Munich, Chemistry Department, Lichtenbergstr. 4, D-85747 Garching, Germany.

出版信息

Org Biomol Chem. 2005 Jun 7;3(11):2062-3. doi: 10.1039/b504079e. Epub 2005 May 4.

DOI:10.1039/b504079e
PMID:15917887
Abstract

1-ethynylpyrene shows remarkable absorption changes upon DNA hybridization when it is covalently attached to the 8-position of guanine. An absorption band at approximately 420 nm is only present in the duplex, exhibits thermal melting behaviour and provides the basis for a molecular beacon together with 1-ethynylpyrene-modified cytosine.

摘要

相似文献

1
1-ethynylpyrene-modified guanine and cytosine as optical labels for DNA hybridization.
Org Biomol Chem. 2005 Jun 7;3(11):2062-3. doi: 10.1039/b504079e. Epub 2005 May 4.
2
1-Ethynylpyrene as a tunable and versatile molecular beacon for DNA.1-乙炔基芘作为一种用于DNA的可调节且通用的分子信标。
Chembiochem. 2004 Jun 7;5(6):865-8. doi: 10.1002/cbic.200300845.
3
Fluorescence quenching by intercalation of a pyrene group tethered to an N4-modified cytosine in duplex DNA.芘基团通过连接到双链 DNA 中 N4 位修饰胞嘧啶的方式进行嵌入导致荧光猝灭。
Photochem Photobiol. 2013 Mar-Apr;89(2):332-5. doi: 10.1111/j.1751-1097.2012.01243.x. Epub 2012 Oct 30.
4
Solution structure of an intramolecular DNA triplex containing an N7-glycosylated guanine which mimics a protonated cytosine.包含模拟质子化胞嘧啶的N7-糖基化鸟嘌呤的分子内DNA三链体的溶液结构。
Biochemistry. 1997 Mar 4;36(9):2659-68. doi: 10.1021/bi962438a.
5
Fluorescent probe for the detection of DNA conformational transition.用于检测DNA构象转变的荧光探针。
Nucleic Acids Symp Ser (Oxf). 2004(48):73-4. doi: 10.1093/nass/48.1.73.
6
2-(1-Ethynylpyrene)-adenosine as a folding probe for RNA - pyrene in or out.2-(1-乙炔基芘基)-腺苷作为 RNA 的折叠探针 - 芘在或不在。
Chembiochem. 2010 Mar 22;11(5):664-72. doi: 10.1002/cbic.200900778.
7
Design of a novel G-quenched molecular beacon: a simple and efficient strategy for DNA sequence analysis.新型G-淬灭分子信标的设计：一种用于DNA序列分析的简单高效策略。
Chem Commun (Camb). 2007 Nov 21(43):4492-4. doi: 10.1039/b709715h. Epub 2007 Aug 29.
8
DNA as a supramolecular scaffold for the helical arrangement of a stack of 1-ethynylpyrene chromophores.DNA作为用于1-乙炔基芘发色团堆叠螺旋排列的超分子支架。
Org Biomol Chem. 2006 Jun 7;4(11):2088-90. doi: 10.1039/b605251g. Epub 2006 May 5.
9
Absorption and fluorescence emission spectroscopic characters of size-expanded yDNA bases and effect of deoxyribose and base pairing.尺寸扩展的yDNA碱基的吸收和荧光发射光谱特征以及脱氧核糖和碱基配对的影响。
J Phys Chem B. 2009 Jan 29;113(4):1173-81. doi: 10.1021/jp8094648.
10
Ultrafast dynamics of 1-ethynylpyrene-modified RNA: a photophysical probe of intercalation.1-乙炔基芘修饰 RNA 的超快动力学：嵌入的光物理探针。
J Phys Chem B. 2010 Sep 9;114(35):11638-45. doi: 10.1021/jp103176q.

引用本文的文献

1
Fluorescent nucleobases as tools for studying DNA and RNA.荧光碱基作为研究 DNA 和 RNA 的工具。
Nat Chem. 2017 Nov;9(11):1043-1055. doi: 10.1038/nchem.2859. Epub 2017 Oct 16.
2
Efficient synthesis of fluorescent alkynyl C-nucleosides via Sonogashira coupling for the preparation of DNA-based polyfluorophores.通过Sonogashira偶联高效合成荧光炔基C-核苷用于制备基于DNA的多荧光团。
Org Biomol Chem. 2016 Jul 6;14(27):6407-12. doi: 10.1039/c6ob01199c.
3
Synthesis and spectral characterization of environmentally responsive fluorescent deoxycytidine analogs.
环境响应型荧光脱氧胞苷类似物的合成与光谱表征
Artif DNA PNA XNA. 2014;5(2):e29174. doi: 10.4161/adna.29174.
4
Conformational Control of Dual Emission by Pyrrolidinyl PNA-DNA Hybrids.吡咯烷基肽核酸-脱氧核糖核酸杂交体对双重发射的构象控制
ChemistryOpen. 2012 Aug;1(4):173-6. doi: 10.1002/open.201200016. Epub 2012 Jul 11.
5
Diarylethene-modified nucleotides for switching optical properties in DNA.二芳烯修饰核苷酸用于 DNA 光学性质的切换。
Beilstein J Org Chem. 2012;8:905-14. doi: 10.3762/bjoc.8.103. Epub 2012 Jun 20.
6
A pyrenyl-PNA probe for DNA and RNA recognition: Fluorescence and UV absorption studies.一种用于DNA和RNA识别的芘基肽核酸探针：荧光和紫外吸收研究。
Artif DNA PNA XNA. 2010 Oct;1(2):83-89. doi: 10.4161/adna.1.2.13899.
7
Fluorescent analogs of biomolecular building blocks: design, properties, and applications.生物分子构件的荧光类似物：设计、性质及应用
Chem Rev. 2010 May 12;110(5):2579-619. doi: 10.1021/cr900301e.