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A Reversible DNA Logic Gate Platform Operated by One- and Two-Photon Excitations.一种由单光子和双光子激发操作的可逆 DNA 逻辑门平台。
Angew Chem Int Ed Engl. 2016 Jan 4;55(1):164-8. doi: 10.1002/anie.201507249. Epub 2015 Nov 4.
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One-Dimensional Multichromophor Arrays Based on DNA: From Self-Assembly to Light-Harvesting.基于 DNA 的一维多色团体系：从自组装到光捕获。
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Environment-responsive aza-BODIPY dyes quenching in water as potential probes to visualize the in vivo fate of lipid-based nanocarriers.环境响应型氮杂 BODIPY 染料在水中的猝灭作用可作为潜在的探针，用于可视化基于脂质的纳米载体的体内命运。
Nanomedicine. 2015 Nov;11(8):1939-48. doi: 10.1016/j.nano.2015.06.013. Epub 2015 Jul 15.
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通过Sonogashira偶联高效合成荧光炔基C-核苷用于制备基于DNA的多荧光团。

Efficient synthesis of fluorescent alkynyl C-nucleosides via Sonogashira coupling for the preparation of DNA-based polyfluorophores.

作者信息

Kölmel Dominik K, Barandun Luzi J, Kool Eric T

机构信息

Department of Chemistry, Stanford University, Stanford, California 94305, USA.

出版信息

Org Biomol Chem. 2016 Jul 6;14(27):6407-12. doi: 10.1039/c6ob01199c.

DOI:10.1039/c6ob01199c
PMID:27296353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4935563/
Abstract

A facile and general procedure for the preparation of alkynyl C-nucleosides with varied fluorophores is presented. Sonogashira coupling was used as a key reaction to conjugate the dyes to an easily accessible ethynyl functionalized deoxyribose derivative. The new C-nucleosides were used for the preparation of DNA-based polyfluorophores.

摘要

本文介绍了一种简便通用的方法来制备带有各种荧光团的炔基碳核苷。Sonogashira偶联反应被用作关键反应，将染料与易于获得的乙炔基官能化脱氧核糖衍生物共轭。这些新型碳核苷用于制备基于DNA的多荧光团。