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Preprandial C2 monitoring of cyclosporine treatment in children with nephrotic syndrome.

作者信息

Fujinaga Shuichiro, Kaneko Kazunari, Takada Masaru, Ohtomo Yoshiyuki, Akashi Shunji, Yamashiro Yuichiro

机构信息

Division of Nephrology, Saitama Children's Medical Center, Shuichiro 2100, Magome Iwatsuki City, Saitama 339, 8551 Iwatsuki, Japan.

出版信息

Pediatr Nephrol. 2005 Sep;20(9):1359-60. doi: 10.1007/s00467-005-1932-7. Epub 2005 May 26.

DOI:10.1007/s00467-005-1932-7
PMID:15918005
Abstract
摘要

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Preprandial C2 monitoring of cyclosporine treatment in children with nephrotic syndrome.肾病综合征患儿环孢素治疗的餐前C2监测
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2
How should microemulsified Cyclosporine A (Neoral) therapy in patients with nephrotic syndrome be monitored?肾病综合征患者的微乳化环孢素A（新山地明）治疗应如何监测？
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3
Cyclosporine C2 monitoring for the treatment of frequently relapsing nephrotic syndrome in children: a multicenter randomized phase II trial.环孢素 C2 监测治疗儿童频繁复发肾病综合征的多中心随机二期临床试验。
Clin J Am Soc Nephrol. 2014 Feb;9(2):271-8. doi: 10.2215/CJN.13071212. Epub 2013 Nov 21.
4
C2 single-point sampling to evaluate cyclosporine exposure in long-term renal transplant recipients.采用C2单点采样法评估长期肾移植受者的环孢素暴露情况。
Transplant Proc. 2001 Nov-Dec;33(7-8):3133-6. doi: 10.1016/s0041-1345(01)02336-3.
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Neoral C2 monitoring in solid organ transplantation.实体器官移植中的新山地明C2监测
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Cyclosporine therapeutic drug monitoring.环孢素治疗药物监测。
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C0/C2 cyclosporine levels monitoring in renal transplantation.肾移植中环孢素C0/C2水平监测
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Greater variability of dose-corrected cyclosporine C2 concentrations in renal recipients with acute rejection.急性排斥反应的肾移植受者中剂量校正环孢素C2浓度的变异性更大。
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Optimization of cyclosporine therapy in the Neoral era: abbreviated AUC, single blood sampling?新山地明时代环孢素治疗的优化：简化的曲线下面积，单次采血？
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Validation of sparse sampling strategies to estimate cyclosporine A area under the concentration-time curve using either a specific radioimmunoassay or high-performance liquid chromatography method.验证使用特定放射免疫分析法或高效液相色谱法估算环孢素 A 浓度-时间曲线下面积的稀疏采样策略。
Ther Drug Monit. 2010 Oct;32(5):586-93. doi: 10.1097/FTD.0b013e3181ed59fe.

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Response predictors and long-term outcomes of preprandial single-daily cyclosporine in children with steroid-dependent nephrotic syndrome.餐前单次每日服用环孢素治疗激素依赖型肾病综合征患儿的反应预测指标及长期预后
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Effectiveness and nephrotoxicity of a 2-year medium dose of cyclosporine in pediatric patients with steroid-dependent nephrotic syndrome: determination of the need for follow-up kidney biopsy.2年中等剂量环孢素治疗小儿激素依赖型肾病综合征的有效性及肾毒性：随访肾活检必要性的判定
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本文引用的文献

1
More stable and reliable pharmacokinetics with preprandial administration of cyclosporine compared with postprandial administration in patients with refractory nephrotic syndrome.与餐后给药相比，难治性肾病综合征患者餐前服用环孢素的药代动力学更稳定可靠。
Pharmacotherapy. 2005 Jan;25(1):52-8. doi: 10.1592/phco.25.1.52.55617.
2
Cyclosporine therapy monitored with abbreviated area under curve in nephrotic syndrome.在肾病综合征中采用简化曲线下面积监测环孢素治疗。
Pediatr Nephrol. 2005 Jan;20(1):25-9. doi: 10.1007/s00467-004-1618-6. Epub 2004 Nov 25.
3
Two-hour post-dose cyclosporin A levels in adolescent renal transplant recipients in the late post-transplant period.
Cyclosporine C2 monitoring for the treatment of frequently relapsing nephrotic syndrome in children: a multicenter randomized phase II trial.
环孢素 C2 监测治疗儿童频繁复发肾病综合征的多中心随机二期临床试验。
Clin J Am Soc Nephrol. 2014 Feb;9(2):271-8. doi: 10.2215/CJN.13071212. Epub 2013 Nov 21.
4
Age effect on whole blood cyclosporine concentrations following oral administration in children with nephrotic syndrome.口服环孢素治疗肾病综合征儿童时全血浓度的年龄效应。
Eur J Pediatr. 2012 Apr;171(4):663-8. doi: 10.1007/s00431-011-1633-0. Epub 2011 Nov 26.
5
Single infusion of rituximab for persistent steroid-dependent minimal-change nephrotic syndrome after long-term cyclosporine.利妥昔单抗单次输注治疗长期环孢素治疗后持续性激素依赖型微小病变肾病综合征
Pediatr Nephrol. 2010 Mar;25(3):539-44. doi: 10.1007/s00467-009-1377-5. Epub 2010 Jan 5.
6
Correlation between finger-prick and venous ciclosporin levels: association with gingival overgrowth and hypertrichosis.指尖采血与静脉血环孢素水平的相关性：与牙龈增生和多毛症的关联。
Pediatr Nephrol. 2007 Dec;22(12):2111-8. doi: 10.1007/s00467-007-0586-z. Epub 2007 Sep 26.
7
Independent risk factors for chronic cyclosporine induced nephropathy in children with nephrotic syndrome.肾病综合征患儿慢性环孢素诱导性肾病的独立危险因素。
Arch Dis Child. 2006 Aug;91(8):666-70. doi: 10.1136/adc.2005.080960. Epub 2006 May 2.
Pediatr Nephrol. 2004 Jun;19(6):667-71. doi: 10.1007/s00467-004-1452-x. Epub 2004 Mar 31.
4
Two-hour post-dose cyclosporine level is a better predictor than trough level of acute rejection of renal allografts.肾移植术后两小时的环孢素血药浓度比谷值浓度更能预测急性排斥反应。
Clin Transplant. 2002 Oct;16(5):378-82. doi: 10.1034/j.1399-0012.2002.02036.x.
5
Cyclosporine absorption profiling and therapeutic drug monitoring using C(2) blood levels in stable renal allograft recipients.使用稳定肾移植受者的C₂血药浓度进行环孢素吸收分析和治疗药物监测。
Transplant Proc. 2002 Aug;34(5):1738-9. doi: 10.1016/s0041-1345(02)03003-8.
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Age-dependent cyclosporine: pharmacokinetics in marrow transplant recipients.年龄依赖性环孢素：骨髓移植受者的药代动力学
Clin Pharmacol Ther. 1986 Oct;40(4):438-43. doi: 10.1038/clpt.1986.204.