Dinwiddie S H, Reich T, Cloninger C R
Department of Psychiatry, Washington University School of Medicine and Jewish Hospital, St Louis, MO 63110.
Compr Psychiatry. 1992 May-Jun;33(3):173-9. doi: 10.1016/0010-440x(92)90026-m.
Information about lifetime intravenous drug use (IVDU) was obtained from 1,062 relatives of hospitalized alcoholics, felons, and control subjects, of whom 92 had a history of IVDU and an additional 230 had a history of substantial, but non-IV drug use. The IVDUs were significantly more likely than all other subjects to have reported experiencing numerous behavioral and social difficulties relating to conduct difficulties, early initiation of substance use, and disrupted living situation before the age of 15. They were also more likely to have exhibited conduct problems than other drug users. In multivariate analyses, four symptoms (fighting in school, juvenile arrest, initiation of cannabis use before 15, or initiation of sexual activity before 15) differentiated IVDUs. A history of greater numbers of these problems was associated with increasing risk for IVDU, both when compared with the total sample and when compared with other drug users.
有关终身静脉注射吸毒（IVDU）的信息来自1062名住院酗酒者、重罪犯和对照受试者的亲属，其中92人有IVDU史，另外230人有大量但非静脉注射吸毒史。与所有其他受试者相比，IVDU者更有可能报告在15岁之前经历过与行为困难、过早开始使用毒品以及生活状况混乱相关的众多行为和社会困难。他们也比其他吸毒者更有可能出现行为问题。在多变量分析中，四种症状（在学校打架、少年被捕、15岁之前开始使用大麻或15岁之前开始性行为）可区分IVDU者。与总样本相比以及与其他吸毒者相比，这些问题数量较多的病史都与IVDU风险增加有关。
