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透析前教育计划(PDEP)对肾脏替代治疗模式的影响。

Influence of a pre-dialysis education programme (PDEP) on the mode of renal replacement therapy.

作者信息

Goovaerts Tony, Jadoul Michel, Goffin Eric

机构信息

Department of Nephrology, Cliniques Universitaires St Luc, Université catholique do Louvain, Av Hippocrate 10, 1200 Brussels, Belgium.

出版信息

Nephrol Dial Transplant. 2005 Sep;20(9):1842-7. doi: 10.1093/ndt/gfh905. Epub 2005 May 26.

Abstract

BACKGROUND

The distribution of renal replacement therapy (RRT) modalities among patients varies from country to country, and is often influenced by non-medical factors. In our department, patients progressing towards end-stage renal disease (ESRD) go through a structured Pre-Dialysis Education Programme (PDEP). The goals of the programme, based on both individualized information session(s) given by an experienced nurse to the patient and family and the use of in-house audio-visual tapes, are to inform on all modalities of RRT, in order to decrease anxiety and promote self-care RRT modalities.

METHODS

To evaluate the influence of our PDEP on the choice of RRT modalities, we retrospectively reviewed the modalities chosen by all consecutive patients starting a first RRT in our institution between December 1994 and March 2000.

RESULTS

Two hundred and forty-two patients started a first RRT during the study period. Fifty-seven patients, median age 66 (24-80) years, were directed towards in-centre haemodialysis (HD) for medical or psycho-social reasons (seven of whom were not involved in the PDEP); the remaining 185 patients, median age 53 (7-81) years, with no major medical complications, went through our PDEP. Eight of them (4%) received a pre-emptive renal transplantation. The therapeutic options of the other 177 patients were as follows: 75 (40%) patients, median age 65 (20-81) years opted for in-centre HD, while 102 patients opted for a self-care modality; 55 (31%) patients, median age 56 (7-77) years, chose peritoneal dialysis, 30 (16%) patients, median age 49 (21-68) years, chose to perform self-care HD in our satellite unit, and 17 (9%) patients, median age 46 (19-70) years, opted for home HD. Interestingly, in the whole cohort of patients, the cause of ESRD was associated with the RRT modality: the proportion of patients with chronic glomerulonephritis or chronic interstitial nephritis on self-care therapy was significantly higher than that of patients with nephrosclerosis, diabetic nephropathy or unknown cause of ESRD.

CONCLUSION

In our centre offering all treatment RRT modalities, a high percentage of patients exposed to a structured PDEP start with a self-care RRT modality. This leaves in-centre HD for patients needing medical and nursing care, or for patients refusing to participate in their treatment. Additional large studies, preferably with a randomized design, should delineate the cost-benefit of such a PDEP on the final choice of a RRT modality.

摘要

背景

肾替代治疗(RRT)模式在不同国家的患者中的分布各不相同,并且常常受到非医学因素的影响。在我们科室,进展至终末期肾病(ESRD)的患者要参加一个结构化的透析前教育项目(PDEP)。该项目的目标是,基于经验丰富的护士向患者及其家属提供的个性化信息以及内部视听资料的使用,告知所有RRT模式,以减轻焦虑并促进自我护理RRT模式。

方法

为了评估我们的PDEP对RRT模式选择的影响,我们回顾性分析了1994年12月至2000年3月期间在我们机构开始首次RRT的所有连续患者所选择的模式。

结果

在研究期间,242例患者开始了首次RRT。57例患者,中位年龄66(24 - 80)岁,因医学或心理社会原因被安排进行中心血液透析(HD)(其中7例未参加PDEP);其余185例患者,中位年龄53(7 - 81)岁,无重大医学并发症,参加了我们的PDEP。其中8例(4%)接受了抢先肾移植。其他177例患者的治疗选择如下:75例(40%)患者,中位年龄65(20 - 81)岁,选择中心HD,而102例患者选择自我护理模式;55例(31%)患者,中位年龄56(7 - 77)岁,选择腹膜透析,30例(16%)患者,中位年龄49(21 - 68)岁,选择在我们的卫星单位进行自我护理HD,17例(9%)患者,中位年龄46(19 - 70)岁,选择家庭HD。有趣的是,在整个患者队列中,ESRD的病因与RRT模式相关:慢性肾小球肾炎或慢性间质性肾炎患者接受自我护理治疗的比例显著高于肾硬化、糖尿病肾病或ESRD病因不明的患者。

结论

在我们这个提供所有RRT治疗模式的中心,接受结构化PDEP的患者中有很大比例开始采用自我护理RRT模式。这就将中心HD留给了需要医疗和护理的患者,或者拒绝参与治疗的患者。还需要更多大型研究,最好采用随机设计,来阐明这种PDEP对RRT模式最终选择的成本效益。

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