Catalanotti P, Catania M R, Lucido M, Martini S, Gallè F, Ortega De Luna L, Rossano F
Dipartimento di Medicina Sperimentale, Sezione di Microbiologia e Microbiologia Clinica, Seconda Università di Napoli, Naples, Italy.
J Chemother. 2005 Apr;17(2):131-7. doi: 10.1179/joc.2005.17.2.131.
Streptococcus pyogenes causes mild infections, such as pharyngitis, and severe infections, such as necrotizing fascitis. In recent years, erythromycin-resistant strains of S. pyogenes have been reported in many countries. In some areas of Italy, increased rates of erythromycin resistance were first observed in the mid-1990s. Here, we report epidemiological T serotyping, invasiveness, erythromycin resistance, and PFGE patterns of 99 S. pyogenes strains isolated at the Laboratory of Clinical Microbiology of the Second University of Naples, Italy. Regarding T serotyping, 26 of 99 strains were W+, 16 strains were U+, 16 were X+, and 14 were agglutinated by anti T serum. A low percentage revealed Y+. Twelve strains were not T serotyped. PFGE patterns showed species polymorphism; however, inside the various serotypes, we demonstrated a fair homogeneity. No correlation among invasiveness and T serotype or PFGE pattern has been shown. Twenty-two of 99 strains were erythromycin-resistant.
化脓性链球菌可引起轻度感染，如咽炎，也可引起严重感染，如坏死性筋膜炎。近年来，许多国家都报告了对红霉素耐药的化脓性链球菌菌株。在意大利的一些地区，20世纪90年代中期首次观察到红霉素耐药率上升。在此，我们报告了从意大利那不勒斯第二大学临床微生物学实验室分离出的99株化脓性链球菌菌株的流行病学T血清分型、侵袭性、红霉素耐药性和脉冲场凝胶电泳（PFGE）图谱。关于T血清分型，99株菌株中有26株为W+，16株为U+，16株为X+，14株被抗T血清凝集。低比例显示为Y+。12株未进行T血清分型。PFGE图谱显示出种内多态性；然而，在不同血清型内部，我们证明了相当的同质性。侵袭性与T血清型或PFGE图谱之间未显示出相关性。99株菌株中有22株对红霉素耐药。
