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体外冲击波碎石术和输尿管镜手术治疗输尿管结石。从文献中我们能了解到哪些关于治疗结果和治疗方法的信息?

Removal of ureteral stones with extracorporeal shock wave lithotripsy and ureteroscopic procedures. What can we learn from the literature in terms of results and treatment efforts?

作者信息

Tiselius Hans-Göran

机构信息

Renal Stone Unit, Department of Urology, Karolinska University Hospital, Huddinge and Karolinska Institutet, Center for Surgical Sciences, 141 86 Stockholm, Sweden.

出版信息

Urol Res. 2005 Jun;33(3):185-90. doi: 10.1007/s00240-005-0462-x. Epub 2005 May 29.

Abstract

A literature review was made to obtain information on the treatment efforts required for a successful removal of ureteral stones when extracorporeal shock wave lithotripsy (ESWL) or ureteroscopic stone extraction or disintegration (URS) were used as primary procedures. Data were collected from 59 reports on ESWL and 23 on URS. The study thereby comprised 20,659 patients primarily treated with ESWL and 5,520 treated with URS. A treatment index (TI) was formulated from the total number of patients (N(TOT)), the number of stone free patients (N(SF)), the number of patients with retreatment (N(RE)), auxiliary procedures (N(AUX)) and general or regional anaesthesia (N(ANE)). The difference between the TI and the efficiency quotients normally used was the incorporation of the factor N(ANE) that reflected the need for general or regional anaesthesia. TI had the following form: TI = N(SF)/(N(TOT) + N(RE) + N(AUX) + N(ANE). When the groups of treated patients were considered in this way, TI was significantly higher for the patients treated with ESWL than for those treated with URS (P = 0.007). The median (range) for the groups of ESWL-treated patients was 0.50 (0.25-0.90) and for patients treated with URS 0.42 (0.26-0.94). For the combined groups of patients, the TI-values were 0.54 and 0.40, respectively. Although the average retreatment for URS was only 2.2% compared with 12.1 percent for ESWL, the need for general/regional anaesthesia was 94.3% and 28.3% in the two groups, respectively. The advantage of a lower rate of retreatment in patients primarily referred to URS was thus obviously counterbalanced by the much higher need for anaesthesia. For ureteral stones treated with ESWL in the author's department using Dornier HM3, MFL 5000, and Modulith SLX lithotripters, stone free rates of 96%, 97% an 95% were associated with TI-values of 0.61, 0.60 and 0.63, respectively. Both ESWL and URS are excellent procedures for the removal of stones from the ureter. In addition to the different degrees of invasiveness, the need for anaesthesia has to be considered in an objective comparison of the two methods.

摘要

进行了一项文献综述,以获取有关当使用体外冲击波碎石术(ESWL)或输尿管镜取石或碎石术(URS)作为主要治疗手段成功清除输尿管结石所需治疗措施的信息。数据收集自59篇关于ESWL的报告和23篇关于URS的报告。该研究共纳入20659例主要接受ESWL治疗的患者和5520例接受URS治疗的患者。根据患者总数(N(TOT))、结石清除患者数(N(SF))、再次治疗患者数(N(RE))、辅助治疗措施(N(AUX))以及全身或区域麻醉患者数(N(ANE))制定了一个治疗指数(TI)。TI与通常使用的效率商数的不同之处在于纳入了反映全身或区域麻醉需求的N(ANE)因素。TI的形式如下:TI = N(SF)/(N(TOT) + N(RE) + N(AUX) + N(ANE)。当以这种方式考虑治疗患者组时,接受ESWL治疗的患者的TI显著高于接受URS治疗的患者(P = 0.007)。接受ESWL治疗患者组的中位数(范围)为0.50(0.25 - 0.90),接受URS治疗患者组的中位数为0.42(0.26 - 0.94)。对于联合患者组,TI值分别为0.54和0.40。尽管URS的平均再次治疗率仅为2.2%,而ESWL为12.1%,但两组中全身/区域麻醉的需求分别为94.3%和28.3%。因此,最初接受URS治疗的患者再次治疗率较低这一优势显然被更高的麻醉需求所抵消。在作者所在科室使用多尼尔HM3、MFL 5000和Modulith SLX碎石机对输尿管结石进行ESWL治疗时,结石清除率分别为96%、97%和95%,对应的TI值分别为0.61、0.60和0.63。ESWL和URS都是清除输尿管结石的优秀治疗方法。在对这两种方法进行客观比较时,除了不同程度的侵入性外,还必须考虑麻醉需求。

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