Saito S, Nishikawa K, Morii T, Narita N, Enomoto M, Ichijo M
Department of Obstetrics and Gynecology, Nara Medical University, Japan.
Immunology. 1992 Apr;75(4):710-2.
T cells of human decidua at an early stage of pregnancy were examined by flow cytometry for the expression of the T-cell-activation antigens CD69, HLA-DR, interleukin-2 receptor-alpha (IL-2R alpha) and IL-2R beta. The decidua contained a small number of T cells and both CD4+ and CD8+ subsets expressed CD69, HLA-DR, IL-2R alpha and IL-2R beta antigens significantly whereas, in peripheral blood, only a small number of T cells expressed these activation antigens. These findings indicate that T cells in the decidua in the first trimester of pregnancy are regionally activated.
采用流式细胞术检测妊娠早期人蜕膜中T细胞激活抗原CD69、HLA-DR、白细胞介素-2受体α（IL-2Rα）和IL-2Rβ的表达。蜕膜中含有少量T细胞，CD4+和CD8+亚群均显著表达CD69、HLA-DR、IL-2Rα和IL-2Rβ抗原，而在外周血中，只有少量T细胞表达这些激活抗原。这些发现表明，妊娠早期蜕膜中的T细胞被局部激活。
