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人蜕膜中的子宫内膜粒细胞与一种自然杀伤(NK)细胞标志物NKH1发生反应。

Endometrial granulocytes in human decidua react with a natural-killer (NK) cell marker, NKH1.

作者信息

Ritson A, Bulmer J N

机构信息

Department of Pathology, University of Leeds, U.K.

出版信息

Immunology. 1987 Oct;62(2):329-31.

Abstract

Lymphoid cells in decidualized uterine endometrium in early human pregnancy may be essential for successful implantation and placentation. Endometrial granulocytes are prominent in early pregnancy decidua and express some T-cell associated surface antigens (CD2+, CD7+), but little is known of their function. We report the unusually intense binding of the natural-killer (NK) cell marker NKH1 to endometrial granulocytes, which contrasts with their lack of reactivity with other NK-cell markers.

摘要

人妊娠早期蜕膜化子宫内膜中的淋巴细胞对于成功着床和胎盘形成可能至关重要。子宫内膜粒细胞在妊娠早期蜕膜中很突出,并表达一些与T细胞相关的表面抗原(CD2 +、CD7 +),但对其功能知之甚少。我们报告了自然杀伤(NK)细胞标志物NKH1与子宫内膜粒细胞异常强烈的结合,这与其对其他NK细胞标志物缺乏反应性形成对比。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b68/1453990/51cf3d4f7c81/immunology00163-0159-a.jpg

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