胰岛移植：进展与挑战。
Islet transplantation: progress and challenge.
作者信息
Gaglia Jason L, Shapiro A M James, Weir Gordon C
机构信息
Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
出版信息
Arch Med Res. 2005 May-Jun;36(3):273-80. doi: 10.1016/j.arcmed.2005.03.014.
For over 30 years, investigators have explored islet transplantation as a logical approach to restoring glucose homeostasis in persons with diabetes. Islet transplantation can currently provide improved glycemic control, relief from recurrent severe hypoglycemia, and potentially insulin independence. In this review, we describe details of the evolution of modern islet transplantation and provide insight into ongoing clinical and basic research efforts to overcome current obstacles for this promising therapy.
30多年来，研究人员一直在探索胰岛移植，将其作为恢复糖尿病患者葡萄糖稳态的合理方法。目前，胰岛移植可以改善血糖控制，缓解反复出现的严重低血糖，并有可能实现胰岛素非依赖。在这篇综述中，我们描述了现代胰岛移植的发展细节，并深入探讨了正在进行的临床和基础研究工作，以克服这一有前景的治疗方法当前面临的障碍。
Zotero 插件