Smitka T A, Bonjouklian R, Perun T J, Hunt A H, Boeck L V, Yao R C
Lilly Research Laboratories, Eli Lilly & Co., Indianapolis, IN 46285.
J Antibiot (Tokyo). 1992 Apr;45(4):433-43. doi: 10.7164/antibiotics.45.433.
A new member of the aurodox family of antibiotics, A83016F, has been isolated from an unidentified actionmycete designated A83016. The structure and relative stereochemistry of A83016F were elucidated by NMR examination of the parent compound and its diacetate derivative. A83016F exhibits only weak antimicrobial activity.
从一株未鉴定的放线菌A83016中分离出了金霉素家族抗生素的一个新成员A83016F。通过对母体化合物及其二乙酸酯衍生物进行核磁共振检查,阐明了A83016F的结构和相对立体化学。A83016F仅表现出微弱的抗菌活性。