Van Houten Bennett, Croteau Deborah L, DellaVecchia Matthew J, Wang Hong, Kisker Caroline
Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, MD D3-01, Research Triangle Park, NC 27709, USA.
Mutat Res. 2005 Sep 4;577(1-2):92-117. doi: 10.1016/j.mrfmmm.2005.03.013.
DNA damage recognition represents a long-standing problem in the field of protein-DNA interactions. This article reviews our current knowledge of how damage recognition is achieved in bacterial nucleotide excision repair through the concerted action of the UvrA, UvrB, and UvrC proteins.
DNA损伤识别是蛋白质-DNA相互作用领域中一个长期存在的问题。本文综述了我们目前对细菌核苷酸切除修复中如何通过UvrA、UvrB和UvrC蛋白的协同作用实现损伤识别的认识。
