Kwong King F
Division of Thoracic Surgery, Greenebaum Cancer Center, University of Maryland School of Medicine, 22 South Greene Street, Room N4E35, Baltimore, MD 21201, USA.
Surg Clin North Am. 2005 Jun;85(3):539-53. doi: 10.1016/j.suc.2005.01.004.
The incidence of esophageal adenocarcinoma is rising in the United States and Western countries. Significant differences exist between esophageal adenocarcinoma and squamous cell carcinoma in the molecular mechanisms responsible for the tumorigenesis process. State-of-the-art techniques such as gene microarrays and proteomics will greatly aid in the development of new therapies targeting specific molecular pathways,ultimately leading to improved survival in patients who have esophageal cancer.
在美国和西方国家，食管腺癌的发病率正在上升。食管腺癌与鳞状细胞癌在肿瘤发生过程的分子机制上存在显著差异。基因微阵列和蛋白质组学等先进技术将极大地有助于开发针对特定分子途径的新疗法，最终提高食管癌患者的生存率。
