Taneja Reshma
Department of Molecular, Cell and Developmental Biology, Mount Sinai School of Medicine, New York, NY 10029, USA.
Sci STKE. 2005 May 31;2005(286):tr17. doi: 10.1126/stke.2862005tr17.
This teaching resource provides lecture notes and slides for a class covering nuclear receptors and is part of the course "Cell signaling systems: a course for graduate students." The lecture begins with a discussion of the structure of nuclear hormone receptors and then proceeds to describe mechanisms of transcriptional regulation, modulation of nuclear receptor activity by phosphorylation, and the role of nuclear receptors in cancer.
本教学资源提供了涵盖核受体课程的讲义和幻灯片,是“细胞信号系统:研究生课程”的一部分。讲座首先讨论核激素受体的结构,然后阐述转录调控机制、磷酸化对核受体活性的调节以及核受体在癌症中的作用。