Conforti Filomena, Statti Giancarlo, Loizzo Monica Rosa, Sacchetti Gianni, Poli Ferruccio, Menichini Francesco
Department of Pharmaceutical Sciences, University of Calabria, Rende, Italy.
Biol Pharm Bull. 2005 Jun;28(6):1098-102. doi: 10.1248/bpb.28.1098.
This study reports on the biological properties, antioxidant and antidiabetic, of two varieties of Amaranthus caudatus seeds, Oscar blanco and Victor red. Oil, squalene and phenolic contents were also determined. Seeds of both investigated varieties were found to possess very different levels of squalene (2.2% in Oscar blanco variety and 7.5% in Victor red variety). Although the antioxidant activity of A. caudatus var. Oscar blanco and A. caudatus var. Victor red statistically did not differ significantly from each other (IC50 values of ethyl acetate extracts were 0.50 mg/ml and 0.62 mg/ml, respectively), significant differences were noticed in relation to antidiabetic activity (inhibition of alpha-amylase, EC 3.2.1.1) of methanolic extracts that showed 50.5% for A. caudatus var. Oscar blanco and 28% for A. caudatus var. Victor red at concentration of 25 microg/ml.
本研究报告了两种尾穗苋种子（奥斯卡布兰科和维克托红）的生物学特性、抗氧化和抗糖尿病特性。同时还测定了油、角鲨烯和酚类物质的含量。研究发现，两个品种的种子角鲨烯含量差异很大（奥斯卡布兰科品种为2.2%，维克托红品种为7.5%）。虽然尾穗苋变种奥斯卡布兰科和尾穗苋变种维克托红的抗氧化活性在统计学上没有显著差异（乙酸乙酯提取物的IC50值分别为0.50毫克/毫升和0.62毫克/毫升），但在甲醇提取物的抗糖尿病活性（抑制α-淀粉酶，EC 3.2.1.1）方面存在显著差异，在25微克/毫升的浓度下，尾穗苋变种奥斯卡布兰科的抑制率为50.5%，尾穗苋变种维克托红的抑制率为28%。
