Jain Nitin B, Guller Ulrich, Pietrobon Ricardo, Bond Thomas K, Higgins Laurence D
Center for Excellence in Surgical Outcomes, Duke University Medical Center, Durham, NC, USA.
Clin Orthop Relat Res. 2005 Jun(435):232-8. doi: 10.1097/01.blo.0000156479.97488.a2.
The objective of our study was to assess the effect of comorbidities (hypertension, diabetes, obesity, and their combinations) on postoperative complications and discharge status in patients having shoulder, hip, and knee arthroplasty (n = 959,839). The association between outcomes and each of the comorbidities was assessed using multivariable logistic regression after adjusting for age, race, household income, gender, and hospital volume. In the multivariable models, postoperative complications were more likely in patients with hypertension, diabetes, or obesity as compared with patients without these comorbidities (for hypertension, odds ratio = 1.07; 95% confidence interval range, 1.04-1.11; for obesity, odds ratio = 1.3; 95% confidence interval range, 1.22-1.41). The likelihood of a nonhomebound disposition of patients on discharge was 1.30 times (95% confidence interval range, 1.27-1.32) in patients with diabetes and 1.45 times (95% confidence interval range, 1.40-1.49) in patients who were obese as compared with patients without these respective comorbidities. Patients with a combination of comorbidities also had a higher likelihood of postoperative complications and nonhomebound discharge. Results of our study showed that hypertension, diabetes, and obesity are independent predictors of increased postoperative complications and non-homebound discharge in patients undergoing shoulder, hip, or knee arthroplasty.
Prognostic study, Level II-1 (retrospective study). See the Guidelines for Authors for a complete description of levels of evidence.
我们研究的目的是评估合并症(高血压、糖尿病、肥胖及其组合)对接受肩、髋和膝关节置换术患者(n = 959,839)术后并发症和出院状态的影响。在对年龄、种族、家庭收入、性别和医院规模进行调整后,使用多变量逻辑回归评估了结局与每种合并症之间的关联。在多变量模型中,与无这些合并症的患者相比,患有高血压、糖尿病或肥胖症的患者术后更易出现并发症(高血压的优势比 = 1.07;95%置信区间范围为1.04 - 1.11;肥胖症的优势比 = 1.3;95%置信区间范围为1.22 - 1.41)。与无相应合并症的患者相比,糖尿病患者出院时非居家安置的可能性为1.30倍(95%置信区间范围为1.27 - 1.32),肥胖患者为1.45倍(95%置信区间范围为1.40 - 1.49)。合并多种合并症的患者术后并发症和非居家出院的可能性也更高。我们的研究结果表明,高血压、糖尿病和肥胖是接受肩、髋或膝关节置换术患者术后并发症增加和非居家出院的独立预测因素。
预后研究,II - 1级(回顾性研究)。有关证据水平的完整描述,请参阅作者指南。