意大利中部拉奎拉地区帕金森病的患病率

Prevalence of Parkinson's disease in the L'Aquila district, central Italy.

作者信息

Totaro R, Marini C, Pistoia F, Sacco S, Russo T, Carolei A

机构信息

Department of Neurology, University of L'Aquila, L'Aquila, Italy.

出版信息

Acta Neurol Scand. 2005 Jul;112(1):24-8. doi: 10.1111/j.1600-0404.2005.00426.x.

DOI:10.1111/j.1600-0404.2005.00426.x

PMID:15932352

Abstract

OBJECTIVE

We estimated the prevalence of Parkinson's disease (PD) in the L'Aquila district.

METHODS

Cases of PD were identified screening all available case sources including general practitioners and antiparkinsonian drug-users by means of pharmacy records. Prevalence of PD was computed considering the prevalence day of December 31, 2001.

RESULTS

On the prevalence day, 682 patients with PD were alive and residing in the L'Aquila district. A total of 354 patients were women and 328 men. The overall crude prevalence rate was 229.3/100,000 (95% CI 212.7-247.1), without any difference between men (227.4/100,000; 95% CI 200.0-257.5) and women (231.1/100,000; 95% CI 202.2-263.1). Prevalence rates increased with age in both sexes and were higher in urban (244.5/100,000; 95% CI 213.7-278.5) than in rural residents (214.7/100,000; 95% CI 189.0-242.9) (SRR = 1.7; 95% CI 1.3-2.1).

CONCLUSIONS

The prevalence of PD in the L'Aquila district was within the range of prevalence rates found in our country and steeply increased with advancing age in both sexes.

摘要

目的

我们对拉奎拉地区帕金森病（PD）的患病率进行了估算。

方法

通过药房记录筛查所有可用病例来源（包括全科医生和抗帕金森病药物使用者）来确定PD病例。计算PD患病率时考虑的患病率日期为2001年12月31日。

结果

在患病率统计日，有682例PD患者存活并居住在拉奎拉地区。其中女性患者354例，男性患者328例。总体粗患病率为229.3/10万（95%可信区间212.7 - 247.1），男性（227.4/10万；95%可信区间200.0 - 257.5）和女性（231.1/10万；95%可信区间202.2 - 263.1）之间无差异。男女患病率均随年龄增长而升高，且城市居民（244.5/10万；95%可信区间213.7 - 278.5）的患病率高于农村居民（214.7/10万；95%可信区间189.0 - 242.9）（标准化相对危险度 = 1.7；95%可信区间1.3 - 2.1）。