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西西里岛埃奥利群岛帕金森病及其他类型帕金森症的患病率

Prevalence of Parkinson's disease and other types of parkinsonism in the Aeolian Archipelago, Sicily.

作者信息

Morgante L, Nicoletti A, Epifanio A, Contrafatto D, Savica R, Lanzafame S, Musolino R, La Spina P, Bonuccelli U, Marconi R, D'Amelio M, Savettieri G, Zappia M

机构信息

Dipartimento di Neuroscienze, Scienze Psichiatriche ed Anestesiologiche, Università di Messina, Messina, Italy.

出版信息

Parkinsonism Relat Disord. 2008 Nov;14(7):572-5. doi: 10.1016/j.parkreldis.2007.11.010. Epub 2008 Mar 5.

Abstract

OBJECTIVE

To estimate prevalence of Parkinson's disease (PD) and other types of parkinsonism in the Aeolian Archipelago, Sicily.

METHODS

We studied the frequency of PD and other types of parkinsonism in the Aeolian Archipelago (population 13,431). All potential cases were identified from available medical information sources. To ensure the completeness of the case-findings, a screening questionnaire was also mailed to residents aged 40 years and over. Subjects were considered prevalent if they fulfilled the SNES diagnostic criteria for PD, on prevalence day (January 1, 2001).

RESULTS

We identified 17 patients with parkinsonism from medical sources, and 4 from mail-survey. Prevalence for all types of parkinsonism was 156.3/100,000 (95% CI 99.4-234.8). Fourteen subjects fulfilled diagnostic criteria for PD giving a crude prevalence of 104.2/100,000 (95% CI 59.4-170.7) and 422.5/100,000 in the population aged 60 years and over.

CONCLUSIONS

Prevalence of all types of parkinsonism and PD found in the Aeolian Archipelago is lower than that previously reported in Sicily.

摘要

目的

评估西西里岛伊奥利亚群岛帕金森病(PD)及其他类型帕金森症的患病率。

方法

我们研究了伊奥利亚群岛(人口13431人)中PD及其他类型帕金森症的发病频率。所有可能的病例均从现有的医疗信息来源中识别出来。为确保病例发现的完整性,还向40岁及以上的居民邮寄了筛查问卷。在患病率调查日(2001年1月1日),若受试者符合PD的SNES诊断标准,则被视为患病。

结果

我们从医疗记录中识别出17例帕金森症患者,从邮件调查中识别出4例。所有类型帕金森症的患病率为156.3/10万(95%置信区间99.4 - 234.8)。14名受试者符合PD诊断标准,粗患病率为104.2/10万(95%置信区间59.4 - 170.7),在60岁及以上人群中为422.5/10万。

结论

伊奥利亚群岛中所有类型帕金森症和PD的患病率低于西西里岛此前报告的患病率。

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