Yamawaki Mika, Kusumi Masayoshi, Kowa Hisanori, Nakashima Kenji
Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Nishi-cho, Yonago, Japan.
Neuroepidemiology. 2009;32(4):263-9. doi: 10.1159/000201565. Epub 2009 Feb 11.
BACKGROUND/AIM: To determine the prevalence and incidence of Parkinson's disease (PD) and compare them with results from our previous studies.
We examined epidemiological characteristics of PD patients using a service-based study in Yonago City, and a door-to-door study in Daisen Town. The prevalence days were April 1, 2004 in Yonago, and April 1, 2003 in Daisen.
In Yonago, we identified 254 PD patients. The crude prevalence was 180.3 (95% CI, 158.1-202.4) per 100,000 population. The adjusted prevalence was 145.8 (95% CI, 145.2-146.5) in 1980, 147.0 (95% CI, 146.3-147.6) in 1992, and 166.8 (95% CI, 166.1-167.5) in 2004, when calculated using the Japanese population in 2004. The crude incidence was 18.4 (95% CI, 11.3-25.5) per 100,000 population per year. The crude incidence in 1980 was 10.2 (95% CI, 4.6-15.8), and the adjusted incidence was 9.8 (95% CI, 4.3-15.3) in 1992, and 10.3 (95% CI, 4.7-15.9) in 2004, when calculated using the population in Yonago in 1980. In Daisen, there were 21 PD patients. The crude prevalence was 306.6 (95% CI, 175.7-437.6) and the adjusted prevalence was 192.6 (95% CI, 191.9-193.8).
The prevalence of PD had increased, primarily because the population had aged. Differences in prevalence between these adjacent areas may have resulted from differences in the methods of investigation.
背景/目的：确定帕金森病（PD）的患病率和发病率，并与我们之前的研究结果进行比较。
我们在米子市采用基于服务的研究方法，在大山镇采用挨家挨户走访的研究方法，对PD患者的流行病学特征进行了调查。患病率调查日期在米子市为2004年4月1日，在大山镇为2003年4月1日。
在米子市，我们共识别出254例PD患者。粗患病率为每10万人口180.3例（95%可信区间，158.1 - 202.4）。当使用2004年的日本人口计算时，调整后的患病率在1980年为145.8例（95%可信区间，145.2 - 146.5），1992年为147.0例（95%可信区间，146.3 - 147.6），2004年为166.8例（95%可信区间，166.1 - 167.5）。粗发病率为每年每10万人口18.4例（95%可信区间，11.3 - 25.5）。1980年的粗发病率为10.2例（95%可信区间，4.6 - 15.8），当使用1980年米子市的人口计算时，1992年的调整发病率为9.8例（95%可信区间，4.3 - 15.3），2004年为10.3例（95%可信区间，4.7 - 15.9）。在大山镇，有21例PD患者。粗患病率为306.6例（95%可信区间，175.7 - 437.6），调整后的患病率为192.6例（95%可信区间，191.9 - 193.8）。
PD的患病率有所上升，主要原因是人口老龄化。这些相邻地区患病率的差异可能是由于调查方法的不同所致
