Terreehorst I, Duivenvoorden H J, Tempels-Pavlica Z, Oosting A J, de Monchy J G R, Bruijnzeel-Koomen C A F M, van Wijk R Gerth
Department of Allergology, Erasmus Medical Centre Rotterdam, Rotterdam, the Netherlands.
Allergy. 2005 Jul;60(7):888-93. doi: 10.1111/j.1398-9995.2004.00677.x.
Environmental control has been put forward as an integral part of the management of house dust mite (HDM) allergy in sensitized patients. To validate this statement allergic disorders involved in HDM allergy--allergic asthma, rhinitis and atopic eczema/dermatitis syndrome (AEDS)--should be taken together and studied in terms of the efficacy of environmental control. Because a generic quality of life questionnaire exceeds the border of disease, this may be used as major outcome parameter.
To study the effects of bedding encasings in HDM allergic patients with asthma, rhinitis and AEDS.
A total of 224 adult HDM allergic patients with rhinitis and/or asthma and/or dermatitis were randomly allocated impermeable or nonimpermeable encasings for mattress, pillow and duvet. Short form 36 (SF-36) was filled in at baseline and after 12 months.
Lower physical (P = 0.01) and emotional (P < 0.001) sumscores were seen in females. Also, the presence of asthma resulted in lower physical sumscore (P = 0.01). However, no effect was seen of encasings on either sumscore.
Bedding encasings do not improve quality of life in a mixed population of subjects with combinations with rhinitis, asthma and atopic dermatitis and sensitized to HDMs.
环境控制已被提出作为过敏性患者屋尘螨(HDM)过敏管理的一个组成部分。为了验证这一说法,应将HDM过敏所涉及的过敏性疾病——过敏性哮喘、鼻炎和特应性湿疹/皮炎综合征(AEDS)——综合起来,并就环境控制的效果进行研究。由于通用的生活质量问卷超出了疾病范畴,因此可将其用作主要结局参数。
研究床上用品外罩对患有哮喘、鼻炎和AEDS的HDM过敏患者的影响。
总共224名患有鼻炎和/或哮喘和/或皮炎的成年HDM过敏患者被随机分配使用床垫、枕头和羽绒被的不透水或透水外罩。在基线时和12个月后填写36项简短健康调查量表(SF-36)。
女性的身体(P = 0.01)和情感(P < 0.001)总分较低。此外,哮喘的存在导致身体总分较低(P = 0.01)。然而,外罩对任何一个总分均无影响。
床上用品外罩并不能改善患有鼻炎、哮喘和特应性皮炎且对HDM过敏的混合人群的生活质量。