性别与单一剪接

Sex and the single splice.

作者信息

Dulac Catherine

机构信息

Howard Hughes Medical Institute, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.

出版信息

Cell. 2005 Jun 3;121(5):664-6. doi: 10.1016/j.cell.2005.05.017.

DOI:10.1016/j.cell.2005.05.017

PMID:15935752

Abstract

Drosophila male courtship offers a unique experimental system to uncover the molecular and neural basis of genetically preprogrammed behavior. In this issue of Cell, Demir and Dickson (2005) and Stockinger et al. (2005) demonstrate that this behavior relies on a single splicing of the fruitless transcript, and on a specific olfactory-based neuronal circuit.

摘要

果蝇的求偶行为提供了一个独特的实验系统，用以揭示基因预编程序行为的分子和神经基础。在本期《细胞》杂志中，德米尔和迪克森（2005年）以及斯托金格等人（2005年）证明，这种行为依赖于无果转录本的单一剪接以及一个特定的基于嗅觉的神经元回路。