Tundis R, Statti G A, Conforti F, Bianchi A, Agrimonti C, Sacchetti G, Muzzoli M, Ballero M, Menichini F, Poli F
Dipartimento di Scienze Farmaceutiche, Università della Calabria, via Pietro Bucci, I-87036 Rende (CS), Italy.
Nat Prod Res. 2005 Jun;19(4):379-87. doi: 10.1080/1478641042000261969.
The biovariability of Helichrysum italicum (Roth) Don grown wild in Calabria and Sardinia (Italy) was reported. This species has been characterized through the detection, isolation and quantitative evaluation of chemical markers (alpha-terpinolene, trans-cariophyllene and neryl acetate) by GC and GC-MS. Antioxidant activity of the methanolic H. italicum extracts using DPPH and beta-carotene bleaching test showed that the Calabrian samples were more active than those from Sardinia. The antibacterial activity of all extracts evidenced the best performance on the Gram positive bacteria particularly on Micrococcus luteus. Moreover, antifungal activity of all extracts was also tested evidencing important results particularly on the phytopathogene fungus Pythium ultimum. In general, as regards the antifungal activity, the extracts from Sardinia were more active than those from Calabria. The phytochemical analysis and the biological activity data suggested a possible use of these plant matrices in alimentary, cosmetic and pharmaceutical fields.
报道了在意大利卡拉布里亚和撒丁岛野生生长的意大利蜡菊（Helichrysum italicum (Roth) Don）的生物变异性。通过气相色谱（GC）和气相色谱 - 质谱联用（GC-MS）对化学标志物（α-松油烯、反式石竹烯和乙酸橙花酯）进行检测、分离和定量评估，对该物种进行了表征。使用DPPH和β-胡萝卜素漂白试验对意大利蜡菊甲醇提取物的抗氧化活性进行检测，结果表明卡拉布里亚的样品比撒丁岛的样品活性更高。所有提取物的抗菌活性表明，其对革兰氏阳性菌表现出最佳效果，尤其是对藤黄微球菌。此外，还测试了所有提取物的抗真菌活性，结果表明对致病疫霉尤其有显著效果。总体而言，就抗真菌活性而言，撒丁岛的提取物比卡拉布里亚的提取物活性更高。植物化学分析和生物活性数据表明，这些植物基质在食品、化妆品和制药领域具有潜在应用价值。
