从 Montenegro 提取的（Roth）G. Don fil.（菊科）的精油的化学成分和抗菌活性。

Chemical composition and antimicrobial activity of essential oil of (Roth) G. Don fil. (Asteraceae) from Montenegro.

机构信息

aDepartment of Public Health and Infectious Diseases, Sapienza University, Rome, Italy.

bDepartment of Drug Chemistry and Technology, Sapienza University, Rome, Italy.

出版信息

Nat Prod Res. 2020 Feb;34(3):445-448. doi: 10.1080/14786419.2018.1538218. Epub 2019 Jan 3.

DOI:10.1080/14786419.2018.1538218

PMID:30602287

Abstract

An experimental investigation on essential oil of a Montenegrin (Roth) G. Don fil. (Asteraceae) is reported. The essential oil was analysed in both liquid and vapour phases. Gas chromatography-mass spectrometry analysis of the liquid oil showed the predominance of sesquiterpenes with -eudesmene (21.65%) and -bisabolene (19.90%) as the major ones. Monoterpene fraction was mainly represented by α-pinene (16.90%) and neryl acetate (10.66%). Head-space technique revealed the vapour phase enriched of monoterpenes with -pinene (78.76%) predominance. The essential oil was tested against methicillin-sensitive (ATCC 29213), (ATCC 25922), (ATCC 14053) and the clinical strains of methicillin-resistant , carbapenem-resistant , carbapenem-resistant and carbapenem-resistant . Interesting fungicidal/bactericidal potency against and carbapenem-resistant was revealed at concentration of 5% .

摘要

报告了对一种黑山（Roth）G. Don fil.（菊科）精油的实验研究。液体和蒸气相都对精油进行了分析。液体油的气相色谱-质谱分析显示，以 - 倍半萜烯（21.65%）和 - 大根香叶烯（19.90%）为主的倍半萜烯占优势。单萜烯馏分主要由 - 蒎烯（16.90%）和乙酸橙花酯（10.66%）组成。顶空技术揭示了蒸气相中富含单萜烯，以 - 蒎烯（78.76%）为主。该精油针对甲氧西林敏感的（ATCC 29213）、（ATCC 25922）、（ATCC 14053）以及耐甲氧西林、耐碳青霉烯、耐碳青霉烯和耐碳青霉烯的临床株进行了测试。在 5%的浓度下，对和耐碳青霉烯的杀菌/抑菌活性表现出有趣的效果。