aDepartment of Public Health and Infectious Diseases, Sapienza University, Rome, Italy.
bDepartment of Drug Chemistry and Technology, Sapienza University, Rome, Italy.
Nat Prod Res. 2020 Feb;34(3):445-448. doi: 10.1080/14786419.2018.1538218. Epub 2019 Jan 3.
An experimental investigation on essential oil of a Montenegrin (Roth) G. Don fil. (Asteraceae) is reported. The essential oil was analysed in both liquid and vapour phases. Gas chromatography-mass spectrometry analysis of the liquid oil showed the predominance of sesquiterpenes with -eudesmene (21.65%) and -bisabolene (19.90%) as the major ones. Monoterpene fraction was mainly represented by α-pinene (16.90%) and neryl acetate (10.66%). Head-space technique revealed the vapour phase enriched of monoterpenes with -pinene (78.76%) predominance. The essential oil was tested against methicillin-sensitive (ATCC 29213), (ATCC 25922), (ATCC 14053) and the clinical strains of methicillin-resistant , carbapenem-resistant , carbapenem-resistant and carbapenem-resistant . Interesting fungicidal/bactericidal potency against and carbapenem-resistant was revealed at concentration of 5% .
报告了对一种黑山(Roth)G. Don fil.(菊科)精油的实验研究。液体和蒸气相都对精油进行了分析。液体油的气相色谱-质谱分析显示,以 - 倍半萜烯(21.65%)和 - 大根香叶烯(19.90%)为主的倍半萜烯占优势。单萜烯馏分主要由 - 蒎烯(16.90%)和乙酸橙花酯(10.66%)组成。顶空技术揭示了蒸气相中富含单萜烯,以 - 蒎烯(78.76%)为主。该精油针对甲氧西林敏感的(ATCC 29213)、(ATCC 25922)、(ATCC 14053)以及耐甲氧西林、耐碳青霉烯、耐碳青霉烯和耐碳青霉烯的临床株进行了测试。在 5%的浓度下,对和耐碳青霉烯的杀菌/抑菌活性表现出有趣的效果。