Kaufmann Stefan H E, Cole Stewart T, Mizrahi Valerie, Rubin Eric, Nathan Carl
Max Plank Institute for Infection Biology, Berlin D10117, Germany.
J Exp Med. 2005 Jun 6;201(11):1693-7. doi: 10.1084/jem.20050842.
Mycobacterium tuberculosis remains a leading cause of morbidity and mortality worldwide. Advances reported at a recent international meeting highlight insights and controversies in the genetics of M. tuberculosis and the infected host, the nature of protective immune responses, adaptation of the bacillus to host-imposed stresses, animal models, and new techniques.
结核分枝杆菌仍然是全球发病和死亡的主要原因。在最近一次国际会议上报告的进展突出了结核分枝杆菌及其感染宿主遗传学方面的见解和争议、保护性免疫反应的性质、该杆菌对宿主施加压力的适应性、动物模型以及新技术。