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新冠病毒感染后播散性肺结核:一例报告

Disseminated Tuberculosis Post COVID-19 Infection: A Case Report.

作者信息

Almatrafi Mohammed A, Awad Khadeeja, Alsahaf Nouf, Tayeb Sarah, Alharthi Adil, Rabie Nada, Fadag Rehab, Alwafi Hassan, Salawati Rayan, Alhindi Aseel K, Salawati Emad, Samannodi Mohammed

机构信息

Department of Pediatrics, Umm Al-Qura University, Makkah, SAU.

Internal Medicine, King Fahad Armed Forces Hospital, Jeddah, SAU.

出版信息

Cureus. 2022 Nov 14;14(11):e31489. doi: 10.7759/cureus.31489. eCollection 2022 Nov.

DOI:10.7759/cureus.31489
PMID:36532934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9749912/
Abstract

Diagnosis of tuberculosis was affected during the coronavirus disease 2019 (COVID-19) pandemic. Several studies have shown an association between tuberculosis reactivation and COVID-19, but disseminated tuberculosis was rare. We present a case of a 17-year-old male hospitalized due to a fever of unknown origin for two weeks. The patient recovered from COVID-19 five weeks ago, and his nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) was negative on current hospitalization. After investigations, diagnosis of disseminated tuberculosis was made by lymph node biopsy and radiological features. The patient was treated with four anti-tuberculosis medications and had a favorable outcome.

摘要

在2019冠状病毒病(COVID-19)大流行期间,结核病的诊断受到了影响。多项研究表明结核病复发与COVID-19之间存在关联,但播散性结核病较为罕见。我们报告一例17岁男性患者,因不明原因发热两周入院。该患者五周前从COVID-19中康复,此次住院时鼻咽严重急性呼吸综合征冠状病毒2(SARS-CoV-2)聚合酶链反应(PCR)检测为阴性。经过检查,通过淋巴结活检和影像学特征诊断为播散性结核病。该患者接受了四种抗结核药物治疗,预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a05/9749912/5c461eb0eb2b/cureus-0014-00000031489-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a05/9749912/4c0341db5c72/cureus-0014-00000031489-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a05/9749912/d388d1ba36a0/cureus-0014-00000031489-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a05/9749912/5c461eb0eb2b/cureus-0014-00000031489-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a05/9749912/4c0341db5c72/cureus-0014-00000031489-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a05/9749912/d388d1ba36a0/cureus-0014-00000031489-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a05/9749912/5c461eb0eb2b/cureus-0014-00000031489-i03.jpg

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本文引用的文献

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Corticosteroids for COVID-19 Therapy: Potential Implications on Tuberculosis.COVID-19 治疗中的皮质类固醇:对结核病的潜在影响。
Int J Mol Sci. 2021 Apr 6;22(7):3773. doi: 10.3390/ijms22073773.
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Emerg Infect Dis. 2020 Nov;26(11):2709-2712. doi: 10.3201/eid2611.203163. Epub 2020 Sep 11.
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Herpes simplex virus and cytomegalovirus reactivations among severe COVID-19 patients.重症 COVID-19 患者中单纯疱疹病毒和巨细胞病毒的再激活
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