含燕麦谷物对美国西班牙裔人群的降胆固醇益处。

Cholesterol-lowering benefits of oat-containing cereal in Hispanic americans.

作者信息

Karmally Wahida, Montez Maria G, Palmas Walter, Martinez Wendy, Branstetter Anita, Ramakrishnan Rajasekhar, Holleran Steve F, Haffner Steven M, Ginsberg Henry N

机构信息

The Irving Center for Clinical Research, Columbia University Medical Center, New York, NY 10032, USA.

出版信息

J Am Diet Assoc. 2005 Jun;105(6):967-70. doi: 10.1016/j.jada.2005.03.006.

DOI:10.1016/j.jada.2005.03.006

PMID:15942550

Abstract

This randomized, controlled trial of cholesterol lowering by an oat bran cereal containing beta glucan vs a corn cereal without soluble fiber in Hispanic Americans was conducted for 11 weeks. One-hundred fifty-two men and women, ages 30 to 70 years, with baseline low-density lipoprotein cholesterol (LDL-C) levels between 120 and 190 mg/dL and triglycerides <400 mg/dL were included. After eating a National Cholesterol Education Program Step 1 diet for 5 weeks, subjects were randomly assigned to the corn or the oat cereal for the next 6 weeks. The daily dose of beta glucan was 3 g. Consumption of oat cereal was associated with a reduction in plasma levels of both total cholesterol (-10.9+/-21.6 mg/dL; -4.5%) and LDL-C (-9.4+/-20.3 mg/dL; -5.3%). Consumption of corn cereal did not affect either total cholesterol (+1.2+/-18.3 mg/dL; 1.1%) or LDL-C (+1.2+/-17.5 mg/dL; 2.2%). Differences between the effects of the two cereals on total cholesterol and LDL-C were significant, P =.0003 and P =.0007, respectively.

摘要

这项针对西班牙裔美国人的随机对照试验，比较了含β-葡聚糖的燕麦麸谷物与不含可溶性纤维的玉米谷物降低胆固醇的效果，试验为期11周。研究纳入了152名年龄在30至70岁之间的男性和女性，其低密度脂蛋白胆固醇（LDL-C）基线水平在120至190mg/dL之间，甘油三酯<400mg/dL。在按照国家胆固醇教育计划第一步饮食方案进食5周后，受试者在接下来的6周被随机分配至食用玉米谷物或燕麦麸谷物组。β-葡聚糖的每日剂量为3g。食用燕麦麸谷物与血浆总胆固醇水平降低（-10.9±21.6mg/dL；-4.5%）和LDL-C降低（-9.4±20.三、mg/dL；-5.3%）相关。食用玉米谷物对总胆固醇（+1.2±18.3mg/dL；1.1%）或LDL-C（+1.2±17.5mg/dL；2.2%）均无影响。两种谷物对总胆固醇和LDL-C影响的差异具有统计学意义，P值分别为0.0003和0.0007。