Burston Benjamin J, Pretorius Pieter M, Ramsden James D
Department of Otolaryngology, Northampton General Hospital, Northampton, UK.
J Laryngol Otol. 2005 Apr;119(4):325-9. doi: 10.1258/0022215054020313.
A triad of retro-ocular pain, discharging ear and abducens nerve palsy, as described by Gradenigo, has been recognized for 150 years. It has traditionally been treated with surgery, but recent advances in imaging, allied with improved antibiotic treatment, allow conservative management of these cases. We present two cases of Gradenigo's syndrome: a 6-year-old child and a 70-year-old man, both without cholesteatoma, who were managed without mastoidectomy. They both had full recovery of abducens nerve function, although this took 6 and 12 weeks, respectively. In order to manage patients with Gradenigo's syndrome safely, accurate diagnostic radiology is essential, and our findings are presented and discussed. With changing medical technology, a review of the diagnostic and treatment options for this rare but serious condition, is timely.
如格拉代尼戈所描述的，眼球后疼痛、耳流脓和展神经麻痹三联征已被认知达150年之久。传统上一直采用手术治疗，但随着影像学的最新进展，加之抗生素治疗的改进，这些病例现在可以采用保守治疗。我们报告两例格拉代尼戈综合征病例：一名6岁儿童和一名70岁男性，两人均无胆脂瘤，均未行乳突切除术而得到妥善治疗。他们的展神经功能均完全恢复，尽管分别耗时6周和12周。为了安全地治疗格拉代尼戈综合征患者，准确的诊断性放射学检查至关重要，我们将展示并讨论我们的研究结果。随着医疗技术的不断变化，对这种罕见但严重病症的诊断和治疗选择进行综述是很及时的。
