Beran Azizullah, Aladamat Nameer, Alchalabi Mustafa, Mhanna Mohammed, Srour Omar, Khader Yasmin, Kayyali Ammar
Department of Internal Medicine, University of Toledo, Toledo, OH, USA.
Department of Neurology, University of Toledo, Toledo, OH, USA.
Eur J Case Rep Intern Med. 2022 Jul 19;9(7):003344. doi: 10.12890/2022_003344. eCollection 2022.
Gradenigo syndrome (GS) was described primarily in the paediatric population, especially in the pre-antibiotic era. GS is rarely reported in the elderly population, especially in the post-antibiotic era. We present the rare case of a 67-year-old man who presented with an incomplete triad of symptoms (without abducens nerve palsy) of GS that failed medical therapy and was successfully treated with surgical intervention (mastoidectomy and petrous apicectomy). Physicians should be familiar with atypical presenting symptoms of GS as it can lead to life-threatening complications, especially in the elderly. GS cases resistant to medical therapy may require prompt appropriate imaging studies and surgical intervention.
Gradenigo syndrome may present with an incomplete triad (without abducens nerve palsy), especially in the post-antibiotic era.Gradenigo syndrome can rarely affect immunocompromised elderly patients.Gradenigo syndrome cases resistant to medical therapy may require prompt appropriate imaging studies and surgical intervention (mastoidectomy and petrous apicectomy).
Gradenigo综合征（GS）主要在儿科人群中被描述，尤其是在抗生素出现之前的时代。GS在老年人群中很少被报道，尤其是在抗生素时代之后。我们报告了一例罕见的67岁男性病例，该患者表现出GS不完全三联征（无展神经麻痹），药物治疗无效，经手术干预（乳突切除术和岩尖切除术）成功治愈。医生应熟悉GS的非典型表现症状，因为它可能导致危及生命的并发症，尤其是在老年人中。对药物治疗耐药的GS病例可能需要及时进行适当的影像学检查和手术干预。
Gradenigo综合征可能表现为不完全三联征（无展神经麻痹），尤其是在抗生素时代之后。Gradenigo综合征很少会影响免疫功能低下的老年患者。对药物治疗耐药的Gradenigo综合征病例可能需要及时进行适当的影像学检查和手术干预（乳突切除术和岩尖切除术）。
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