Durvasula V S P, Brewis C, Syeda F, Leong P
Department of Otolaryngology, Edith Cavell Hospital, Peterborough, UK.
J Laryngol Otol. 2005 May;119(5):348-51. doi: 10.1258/0022215053945859.
The objective of this study was to assess the efficacy of topical lignocaine in reducing the pain of pack removal after nasal surgery. Fifty-eight patients with Merocel nasal packs in situ after nasal surgery were randomized to receive 10 ml of either 2 per cent lignocaine or 0.9 per cent saline on the packs 10 minutes prior to their removal and the pain experienced on their removal was recorded on a visual analogue scale. The median pain score was 3.4 in the lignocaine group and 2.9 in the saline group with no statistical evidence of a difference between the two groups. There was no statistical evidence of an association between the group and the operation performed, the use of intra-operative Moffat's solution or the use of post-operative oral analgesia. We conclude that lignocaine used in this way does not reduce the pain of pack removal after nasal surgery.
本研究的目的是评估局部使用利多卡因减轻鼻腔手术后取出填塞物时疼痛的疗效。58例鼻腔手术后鼻腔内留置美罗可填塞物的患者被随机分为两组,在取出填塞物前10分钟,一组在填塞物上滴注10毫升2%利多卡因,另一组滴注10毫升0.9%生理盐水,取出填塞物时的疼痛程度采用视觉模拟评分法记录。利多卡因组的疼痛评分中位数为3.4,生理盐水组为2.9,两组之间无统计学差异。两组与所施行的手术、术中使用莫法特溶液或术后使用口服镇痛药之间均无统计学关联。我们得出结论,以这种方式使用利多卡因并不能减轻鼻腔手术后取出填塞物时的疼痛。