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4%利多卡因溶液用于移除美洛赛鼻腔填塞物的前瞻性随机对照研究

A prospective randomized controlled study of 4% lignocaine solution in Merocel nasal pack removal.

作者信息

Lavy J A, Small G V, Jay N, Radcliffe G J

机构信息

Department of ENT/Head and Neck Surgery, Royal Free Hospital, London, United Kingdom.

出版信息

Rhinology. 1996 Dec;34(4):219-21.

PMID:9050100
Abstract

Packing of the nasal cavity following intranasal surgery is still widely practised. The removal of this packing is invariably associated with a significant amount of pain. We designed a prospective randomised case-controlled study to look at the efficacy of 4% lignocaine solution as a potential analgesic in the removal of Merocel nasal packs. Each patient had bilateral packs and acted as his or her own control with one pack being rehydrated with lignocaine and the other with saline. We found that there was a reduction in the level of discomfort experienced on the side rehydrated with lignocaine, although this reduction did not reach significance. We emphasize the importance of rehydration of these packs prior to removal.

摘要

鼻内手术后鼻腔填塞仍被广泛应用。取出这种填塞物总是伴随着大量疼痛。我们设计了一项前瞻性随机病例对照研究,以观察4%利多卡因溶液作为一种潜在镇痛药在取出美罗海绵鼻腔填塞物时的疗效。每位患者双侧均有填塞物,且以自身作为对照,一侧填塞物用利多卡因复水,另一侧用生理盐水复水。我们发现,用利多卡因复水一侧在取出填塞物时所经历的不适程度有所降低,尽管这种降低未达到显著水平。我们强调在取出这些填塞物之前进行复水的重要性。

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