Crum R M, Bucholz K K, Helzer J E, Anthony J C
Department of Epidemiology, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205.
Am J Epidemiol. 1992 May 1;135(9):989-99. doi: 10.1093/oxfordjournals.aje.a116411.
In this analysis of prospectively gathered data, the authors sought to estimate the degree to which risk of alcohol abuse and dependence might be elevated among adults who attended but did not complete high school and among those who attended college without earning a degree. Study subjects were selected in 1980-1984 by taking probability samples of adult household residents at five sites of the Epidemiologic Catchment Area Program: New Haven, Connecticut; Baltimore, Maryland; St. Louis, Missouri; Durham-Piedmont, North Carolina; and Los Angeles, California. At baseline, participants completed standardized interviews that measured sociodemographic variables and assessed whether they had met diagnostic criteria for currently or formerly active alcohol abuse-dependence syndromes. The interviews were readministered 1 year later to identify incident cases among the 13,673 participants. After subjects were sorted into risk sets by age and residence census tract and after persons with a prior history of alcohol abuse or dependence were excluded, there were in 156 risk sets 160 incident cases and 526 subjects at risk for future occurrence of alcohol syndromes. Compared with adults who had earned a college degree, those who had attended high school without completion were at increased risk (relative risk (RR) = 6.23, 95 percent confidence interval (CI) 2.41-16.09) as were adults who had attended college without earning a degree (RR = 3.25, 95 percent CI 1.36-7.76). In contrast, risk of alcohol disorders among adults with a high school diploma but no college was not reliably greater than the level of risk for those with a college degree (RR = 1.88, 95 percent CI 0.79-4.47).
在这项对前瞻性收集数据的分析中,作者试图评估在未完成高中学业的成年人以及上过大学但未获得学位的成年人中,酒精滥用和酒精依赖风险可能升高的程度。研究对象于1980年至1984年通过对流行病学集水区项目五个地点的成年家庭居民进行概率抽样选取:康涅狄格州纽黑文;马里兰州巴尔的摩;密苏里州圣路易斯;北卡罗来纳州达勒姆 - 皮埃蒙特;以及加利福尼亚州洛杉矶。在基线时,参与者完成了标准化访谈,这些访谈测量了社会人口统计学变量,并评估他们是否符合当前或既往活跃的酒精滥用 - 依赖综合征的诊断标准。一年后再次进行访谈以确定13673名参与者中的新发病例。在按年龄和居住普查区将受试者分类到风险组中,并排除有酒精滥用或依赖既往史的人之后,在156个风险组中有160例新发病例和526名有未来发生酒精综合征风险的受试者。与获得大学学位的成年人相比,未完成高中学业的成年人风险增加(相对风险(RR)= 6.23,95%置信区间(CI)2.41 - 16.09),上过大学但未获得学位的成年人也是如此(RR = 3.25,95%CI 1.36 - 7.76)。相比之下,有高中文凭但未上过大学的成年人中酒精障碍的风险并不比有大学学位的人风险水平高(RR = 1.88,95%CI 0.79 - 4.47)。