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阴道脱垂严重程度与症状及生活质量的关系。

The relationship of vaginal prolapse severity to symptoms and quality of life.

作者信息

Digesu G Alessandro, Chaliha Charlotte, Salvatore Stefano, Hutchings Anna, Khullar Vik

机构信息

Academic Department of Obstetrics and Gynaecology, Urogynaecology Unit, Imperial College, St Mary's Hospital, London, UK.

出版信息

BJOG. 2005 Jul;112(7):971-6. doi: 10.1111/j.1471-0528.2005.00568.x.

DOI:10.1111/j.1471-0528.2005.00568.x
PMID:15958002
Abstract

OBJECTIVE

To assess the relationship and location of vaginal prolapse severity to symptoms and quality of life.

DESIGN

A prospective observational study.

SETTING

Urogynaecology Unit, Imperial College, St Mary's Hospital, London.

POPULATION

Women with and without symptoms of vaginal prolapse.

METHODS

All women completed a validated Prolapse Quality of Life (P-QOL) questionnaire. This included a urinary, bowel and sexual symptom questionnaire. All women were examined using the Pelvic Organ Prolapse Quantification system (POP-Q). POP-Q scores in those with and without prolapse symptoms were compared. Urinary and bowel symptoms and sexual function were compared and related to prolapse severity and location.

MAIN OUTCOME MEASURES

POP-Q scores, P-QOL scores, urinary and bowel symptoms and sexual function.

RESULTS

Three hundred and fifty-five women were recruited-233 symptomatic and 122 asymptomatic of prolapse. The median P-QOL domain scores ranged between 42-100 in symptomatic women and 0-25 in those who were asymptomatic. The stage of prolapse was significantly higher in those symptomatic of prolapse (P < 0.001) except for perineal body (PB) measurement. Urinary symptoms were not correlated with uterovaginal prolapse severity whereas bowel symptoms were strongly associated with posterior vaginal wall prolapse. Cervical descent was found to have a relationship with sexual dysfunction symptoms.

CONCLUSIONS

Women who present with symptoms specific to pelvic organ prolapse demonstrate greater degrees of pelvic relaxation than women who present without symptoms. Prolapse severity and quality of life scores are significantly different in those women symptomatic of prolapse. There was a stronger relationship between posterior prolapse and bowel symptoms than anterior prolapse and urinary symptoms. Sexual dysfunction was related to cervical descent.

摘要

目的

评估阴道脱垂严重程度与症状及生活质量之间的关系和部位。

设计

一项前瞻性观察性研究。

地点

伦敦圣玛丽医院帝国理工学院泌尿妇科病房。

研究对象

有和没有阴道脱垂症状的女性。

方法

所有女性均完成一份经过验证的脱垂生活质量(P-QOL)问卷。这包括一份泌尿、肠道和性症状问卷。所有女性均使用盆腔器官脱垂量化系统(POP-Q)进行检查。比较有和没有脱垂症状者的POP-Q评分。比较泌尿和肠道症状以及性功能,并将其与脱垂严重程度和部位相关联。

主要观察指标

POP-Q评分、P-QOL评分、泌尿和肠道症状以及性功能。

结果

招募了355名女性——233名有症状的脱垂患者和122名无症状的脱垂患者。有症状女性的P-QOL领域评分中位数在42 - 100之间,无症状女性的评分中位数在0 - 25之间。除会阴体(PB)测量外,有脱垂症状者的脱垂分期明显更高(P < 0.001)。泌尿症状与子宫阴道脱垂严重程度无关,而肠道症状与阴道后壁脱垂密切相关。发现宫颈下降与性功能障碍症状有关。

结论

出现盆腔器官脱垂特定症状的女性比没有症状的女性表现出更大程度的盆腔松弛。有脱垂症状的女性,其脱垂严重程度和生活质量评分有显著差异。后位脱垂与肠道症状之间的关系比前位脱垂与泌尿症状之间的关系更强。性功能障碍与宫颈下降有关。

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