Houston Mark C, Basile Jan, Bestermann William H, Egan Brent, Lackland Daniel, Hawkins Ralph G, Moore Michael A, Reed James, Rogers Philip, Wise Daniel, Ferrario Carlos M
Consortium for Southeastern Hypertension Control (COSEHC) and Vanderbilt University School of Medicine and St. Thomas Hospital, Nashville, Tennessee, USA.
Am J Med Sci. 2005 Jun;329(6):276-91. doi: 10.1097/00000441-200506000-00008.
An expanded occurrence of the metabolic syndrome in the U.S. population, especially in the Southeastern United States, has raised awareness of a need to revise our approach to the management of global cardiovascular risk factors while underscoring a need for more aggressive interventions and prevention measures. In defining the components of the metabolic syndrome and the interrelationship among obesity, hypertension, dyslipidemia, and insulin resistance, a basic framework for the medical management of this syndrome has been defined. In Part I of the consensus report prepared by the Workgroup on Medical Guidelines of the Consortium for Southeastern Hypertension Control (COSEHC), we analyze the components of the metabolic syndrome, discuss its pathophysiology, and recommend an approach to the quantitative analysis of the risk factors contributing to excess cardiovascular death in the region.
代谢综合征在美国人群中，尤其是美国东南部地区，呈现出扩大化的态势，这提高了人们对于修订全球心血管危险因素管理方法的认识，同时也凸显了采取更积极干预措施和预防措施的必要性。在界定代谢综合征的组成部分以及肥胖、高血压、血脂异常和胰岛素抵抗之间的相互关系时，已经确定了该综合征医学管理的基本框架。在东南高血压控制联盟（COSEHC）医学指南工作组编写的共识报告第一部分中，我们分析了代谢综合征的组成部分，讨论了其病理生理学，并推荐了一种对该地区导致心血管死亡过多的危险因素进行定量分析的方法。
