一项比较腰麻-硬膜外联合麻醉与全身麻醉用于肾移植手术的随机研究。

A randomized study comparing combined spinal epidural or general anesthesia for renal transplant surgery.

作者信息

Hadimioglu N, Ertug Z, Bigat Z, Yilmaz M, Yegin A

机构信息

Department of Anesthesiology, Akdeniz University, Dumlupinar Bulvari, Antalya 07050, Turkey.

出版信息

Transplant Proc. 2005 Jun;37(5):2020-2. doi: 10.1016/j.transproceed.2005.03.034.

DOI:10.1016/j.transproceed.2005.03.034

PMID:15964328

Abstract

INTRODUCTION

The appropriate anesthesia for renal transplantation requires minimal toxicity for patients and for the transplanted organ, as well as sufficient pain relief and maintenance of vital functions. The aim of this study was to determine how the anesthetic technique influences the outcome in patients after renal transplantation in terms of preoperative and intraoperative hemodynamic changes and blood gas changes.

METHODS

Fifty adult patients undergoing renal transplantation were randomly divided into two groups receiving standardized general anesthesia or combined spinal and epidural anesthesia.

RESULTS

Demographically both groups were similar. Total anesthesia time (202 +/- 53 vs 186 +/- 37 minutes) and surgical time (191 +/- 52 vs 162 +/- 31 minutes) did not differ between the groups. The heart rate and systolic blood pressure values of the groups as measured before induction and 5, 15, 20, 30, as well as 60 minutes thereafter did not differ between the groups. Neither the frequency of bradycardia (four vs two) nor of hypotension (six vs four) during anesthesia differed between regional versus general anesthesia groups.

CONCLUSION

Regional is an important alternative to general anesthesia during renal transplantation surgery in adult patients.

摘要

引言

肾移植的合适麻醉需要对患者和移植器官毒性最小，同时要有足够的疼痛缓解和维持重要功能。本研究的目的是确定麻醉技术如何在术前和术中血流动力学变化及血气变化方面影响肾移植患者的预后。

方法

50例接受肾移植的成年患者被随机分为两组，分别接受标准化全身麻醉或腰麻联合硬膜外麻醉。

结果

两组在人口统计学上相似。两组的总麻醉时间（202±53分钟对186±37分钟）和手术时间（191±52分钟对162±31分钟）无差异。两组在诱导前、诱导后5、15、20、30以及此后60分钟测量的心率和收缩压值无差异。区域麻醉组和全身麻醉组在麻醉期间心动过缓（4例对2例）和低血压（6例对4例）的发生率均无差异。