Eryilmaz M M, Ozdemir C, Yurtman F, Cilli A, Karaman T
Department of Psychiatry, Akdeniz University School of Medicine, University Hospital, Dumlupinar Bulvari Campus, Antalya 07058, Turkey.
Transplant Proc. 2005 Jun;37(5):2072-6. doi: 10.1016/j.transproceed.2005.03.084.
Sleep and sleep-related disorders are common among end-stage renal disease patients. In the general population and hemodialysis patients, insomnia impairs health-related quality of life (HRQOL). The aims of this study were to examine the prevalence of sleep problems among renal transplantation patients and the relationship between the quality of sleep and the HRQOL.
Pittsburgh Sleep Quality Index (PSQI) for measuring quality of sleep, WHOQOL-BREF for quality of life, and Beck Depression Inventory (BDI) were applied to 100 renal transplant patients.
Thirty (30%) subjects were "poor sleepers" (global PSQI > 5). Poor sleepers were younger (mean age: 31 vs 37); less educated (mean years of education: 7.80 vs 9.55), and more depressed (mean BDI scores 13.63 vs 7.18). There were significant inverse correlations between global PSQI and physical health (r = -0.31; P < .001) and psychological state (r = -.20; P = .04) with a significant correlation with BDI scores (r = .36; P < .001). The BDI score (P < .001) was the only significant factor of physical health, psychological state, and social functioning. BDI score (P < .001) and education (P < .022) were significant predictors of environmental conditions.
Sleep problems are not as common among transplant as dialysis patients, but still higher than the general population. Poor sleep seems to be a part of depressive symptomatology. Severity of depression and lower education were more negatively effective factors on the quality of life of these patients than the quality of sleep.
睡眠及与睡眠相关的障碍在终末期肾病患者中很常见。在普通人群和血液透析患者中,失眠会损害健康相关生活质量(HRQOL)。本研究的目的是调查肾移植患者睡眠问题的患病率以及睡眠质量与健康相关生活质量之间的关系。
对100名肾移植患者应用匹兹堡睡眠质量指数(PSQI)来测量睡眠质量,应用世界卫生组织生活质量简表(WHOQOL - BREF)来评估生活质量,并应用贝克抑郁量表(BDI)。
30名(30%)受试者为“睡眠不佳者”(PSQI总分>5)。睡眠不佳者更年轻(平均年龄:31岁对37岁);受教育程度更低(平均受教育年限:7.80年对9.55年),且抑郁程度更高(平均BDI得分13.63对7.18)。PSQI总分与身体健康(r = -0.31;P <.001)和心理状态(r = -.20;P =.04)之间存在显著负相关,与BDI得分存在显著相关性(r =.36;P <.001)。BDI得分(P <.001)是身体健康、心理状态和社会功能的唯一显著因素。BDI得分(P <.001)和受教育程度(P <.022)是环境状况的显著预测因素。
睡眠问题在移植患者中不如透析患者常见,但仍高于普通人群。睡眠不佳似乎是抑郁症状的一部分。与睡眠质量相比,抑郁严重程度和低教育程度对这些患者的生活质量有更负面的影响。