Cazabon S, Groenewald C, Pearce I A, Wong D
St Paul's Eye Unit, Royal Liverpool University Hospital, Prescott Street, Liverpool, L7 8XP, UK.
Br J Ophthalmol. 2005 Jul;89(7):799-802. doi: 10.1136/bjo.2004.053561.
To investigate the cause of visual loss following removal of intraocular silicone oil in patients who underwent vitrectomies for retinal detachment or giant retinal tear.
The clinical records of three cases with visual loss following removal of silicone oil were reviewed. Investigations carried out included fundus fluorescein angiogram, optical coherence tomography, and electrophysiological studies.
Visual acuities dropped from 6/9 to 6/36 in two cases and 6/24 to 3/24 in the third. None of the three cases had macula detachment at any stage. Fundus fluorescein angiogram and optical coherence tomography were normal in all cases. Pattern electroretinogram showed reduced amplitudes of the P50 and N95 components. Multifocal electroretinogram indicated a selective damage to the central part of the macula.
The results suggest that the abnormality arises predominantly in the central part of the macula, especially the outer and middle layers. However, the exact mechanism still remains obscure.
探讨因视网膜脱离或巨大视网膜裂孔接受玻璃体切除术的患者在眼内硅油取出后视力丧失的原因。
回顾了3例硅油取出后视力丧失患者的临床记录。进行的检查包括眼底荧光血管造影、光学相干断层扫描和电生理研究。
2例患者的视力从6/9降至6/36，第3例从6/24降至3/24。3例患者在任何阶段均未发生黄斑脱离。所有病例的眼底荧光血管造影和光学相干断层扫描均正常。图形视网膜电图显示P50和N95成分的振幅降低。多焦视网膜电图表明黄斑中心部分有选择性损伤。
结果表明，异常主要发生在黄斑中心部分，尤其是外层和中层。然而，确切机制仍不清楚。
