• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Interleukin-5, eosinophils, and disease.

作者信息

Sanderson C J

机构信息

Searle Research Group, Dept. of Biochemistry, Oxford, UK.

出版信息

Blood. 1992 Jun 15;79(12):3101-9.

PMID:1596561
Abstract
摘要

相似文献

1
Interleukin-5, eosinophils, and disease.白细胞介素-5、嗜酸性粒细胞与疾病。
Blood. 1992 Jun 15;79(12):3101-9.
2
Airway hyperresponsiveness: first eosinophils and then neuropeptides.气道高反应性:先是嗜酸性粒细胞,然后是神经肽。
Int J Immunopharmacol. 1997 Sep-Oct;19(9-10):517-27. doi: 10.1016/s0192-0561(97)00085-4.
3
Eosinophils and the lung.嗜酸性粒细胞与肺。
Monaldi Arch Chest Dis. 1994 Jun;49(3):221-6.
4
Interleukin-5: a proeosinophil cytokine mediator of inflammation in asthma and a target for antisense therapy.白细胞介素-5:哮喘炎症中嗜酸性粒细胞的一种促炎细胞因子介质及反义疗法的靶点。
Allergy Asthma Proc. 1998 Sep-Oct;19(5):257-61. doi: 10.2500/108854198778557782.
5
Eosinophils negatively regulate eosinophilopoiesis by decreasing IL-5 levels.嗜酸性粒细胞通过降低白细胞介素-5水平对嗜酸性粒细胞生成进行负调控。
Int Arch Allergy Immunol. 1996;111 Suppl 1:2-4. doi: 10.1159/000237403.
6
Eosinophils, eosinophilic cytokines (interleukin-5), and antieosinophilic therapy in asthma.哮喘中的嗜酸性粒细胞、嗜酸性粒细胞细胞因子(白细胞介素-5)及抗嗜酸性粒细胞治疗
Curr Opin Pulm Med. 2002 Jan;8(1):33-8. doi: 10.1097/00063198-200201000-00006.
7
Molecular mechanisms of defective eosinophil apoptosis in diseases associated with eosinophilia.
Int Arch Allergy Immunol. 1997 May-Jul;113(1-3):206-8. doi: 10.1159/000237548.
8
Cellular and molecular regulation of eosinophil trafficking to the lung.
Immunol Cell Biol. 1998 Oct;76(5):454-60. doi: 10.1046/j.1440-1711.1998.00766.x.
9
Pulmonary biology of anti-interleukin 5 antibodies.抗白细胞介素5抗体的肺生物学
Mem Inst Oswaldo Cruz. 1997;92 Suppl 2:69-73. doi: 10.1590/s0074-02761997000800011.
10
Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice.嗜酸性粒细胞趋化因子通过一种独特的受体触发嗜酸性粒细胞选择性趋化作用和钙流,并在小鼠存在白细胞介素5的情况下诱导肺部嗜酸性粒细胞增多。
Mol Med. 1996 May;2(3):334-48.

引用本文的文献

1
Defining and targeting mechanisms of eosinophilic inflammation in a new era of severe asthma treatment.在重度哮喘治疗的新时代中定义并靶向嗜酸性粒细胞炎症机制。
J Clin Invest. 2024 Jun 17;134(12):e182410. doi: 10.1172/JCI182410.
2
Phenotypic Shift of an Inflammatory Eosinophil Subset into a Steady-State Resident Phenotype after 2 Years of Vaccination against IL-5 in Equine Insect Bite Hypersensitivity.在针对马蚊虫叮咬超敏反应进行抗白细胞介素-5疫苗接种2年后,炎症性嗜酸性粒细胞亚群向稳态驻留表型的表型转变。
Vet Sci. 2024 Oct 5;11(10):476. doi: 10.3390/vetsci11100476.
3
Effects of Mepolizumab in the treatment of type 2 CRSwNP: a real-life clinical study.
美泊利单抗治疗2型慢性鼻-鼻窦炎伴鼻息肉的效果:一项真实世界临床研究
Eur Arch Otorhinolaryngol. 2025 Jan;282(1):265-272. doi: 10.1007/s00405-024-09027-8. Epub 2024 Oct 15.
4
The Role of Eosinophils in Liver Disease.嗜酸性粒细胞在肝脏疾病中的作用。
Cell Mol Gastroenterol Hepatol. 2025;19(2):101413. doi: 10.1016/j.jcmgh.2024.101413. Epub 2024 Sep 28.
5
Long-term effects of mepolizumab in patients with severe eosinophilic asthma: a 6-year real-life experience.美泊利珠单抗治疗重度嗜酸性粒细胞性哮喘患者的长期疗效:6年真实世界经验
Front Pharmacol. 2024 Aug 8;15:1449220. doi: 10.3389/fphar.2024.1449220. eCollection 2024.
6
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease.嗜酸性粒细胞的空间适应性及其在稳态、感染和疾病中的新兴作用。
Nat Rev Immunol. 2024 Dec;24(12):858-877. doi: 10.1038/s41577-024-01048-y. Epub 2024 Jul 9.
7
A Potential Role of Interleukin-5 in the Pathogenesis and Progression of Amyotrophic Lateral Sclerosis: A New Molecular Perspective.白细胞介素-5 在肌萎缩侧索硬化症发病机制和进展中的潜在作用:新的分子视角。
Int J Mol Sci. 2024 Mar 28;25(7):3782. doi: 10.3390/ijms25073782.
8
Protective effect of Achyranthes aspera against compound 48/80, histamine and ovalbumin-induced allergic disorders in murine model.牛膝对复合 48/80、组胺和卵清蛋白诱导的过敏性疾病模型小鼠的保护作用。
Mol Biol Rep. 2024 Jan 25;51(1):202. doi: 10.1007/s11033-023-09137-2.
9
Which inflammatory marker, between systemic immune-inflammation index and neutrophil to eosinophil ratio, is associated with Peyronie's disease and are there any implications for a better understanding of its mechanisms?在全身免疫炎症指数和中性粒细胞与嗜酸性粒细胞比值这两种炎症标志物中,哪一种与佩罗尼氏病相关,对更好地理解其发病机制有何启示?
Basic Clin Androl. 2023 Dec 19;33(1):38. doi: 10.1186/s12610-023-00213-y.
10
Successful immunosuppressant-free treatment of a drug-induced sarcoidosis-like reaction caused by dupilumab.度普利尤单抗引起的药物性结节病样反应的无免疫抑制剂成功治疗。
Respir Med Case Rep. 2023 May 31;44:101883. doi: 10.1016/j.rmcr.2023.101883. eCollection 2023.