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First description of DHA-1 ampCbeta-lactamase in Proteus mirabilis.

作者信息

Bidet P, Verdet C, Gautier V, Bingen E, Arlet G

机构信息

Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant (EA 3105), Université Denis Diderot-Paris VII, Service de Microbiologie, Hôpital Robert Debré, Paris, France.

出版信息

Clin Microbiol Infect. 2005 Jul;11(7):591-2. doi: 10.1111/j.1469-0691.2005.01178.x.

DOI:10.1111/j.1469-0691.2005.01178.x
PMID:15966982
Abstract

This report describes the first occurrence of the DHA-1 ampCbeta-lactamase gene in Proteus mirabilis. The organism was isolated from the vaginal flora of a pregnant woman in a French hospital. The DHA-1 beta-lactamase gene was identified on the basis of phenotypic characteristics, PCR amplification and sequencing. Antagonism between cefoxitin and the other cephalosporins suggested inducible production of the DHA-1 enzyme.

摘要

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CMY-16, a novel acquired AmpC-type beta-lactamase of the CMY/LAT lineage in multifocal monophyletic isolates of Proteus mirabilis from northern Italy.
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