Vourli S, Tsorlini H, Katsifa H, Polemis M, Tzouvelekis L S, Kontodimou A, Vatopoulos A C
Department of Microbiology, National School of Public Health, Athens, Greece.
Clin Microbiol Infect. 2006 Jul;12(7):691-4. doi: 10.1111/j.1469-0691.2006.01489.x.
Seven genetically related Proteus mirabilis clinical isolates from a hospital in Thessaloniki, Greece, exhibited decreased susceptibility to imipenem and carried a bla(VIM-1) metallo-beta-lactamase gene. PCR mapping revealed that bla(VIM-1) was part of a class 1 integron that was probably located in the chromosome and also included the aacA7, dhfr and aadA genes. This is the first description of the bla(VIM-1) metallo-beta-lactamase gene in P. mirabilis.
从希腊塞萨洛尼基一家医院分离出的7株基因相关的奇异变形杆菌临床菌株，对亚胺培南的敏感性降低，并携带bla(VIM-1)金属β-内酰胺酶基因。PCR定位显示bla(VIM-1)是1类整合子的一部分，该整合子可能位于染色体上，还包括aacA7、dhfr和aadA基因。这是首次在奇异变形杆菌中描述bla(VIM-1)金属β-内酰胺酶基因。
