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Calcitonin treatment in lumbar spinal stenosis: a randomized, placebo-controlled, double-blind, cross-over study with one-year follow-up.

作者信息

Eskola A, Pohjolainen T, Alaranta H, Soini J, Tallroth K, Slätis P

机构信息

Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland.

出版信息

Calcif Tissue Int. 1992 May;50(5):400-3. doi: 10.1007/BF00296769.

DOI:10.1007/BF00296769
PMID:1596776
Abstract

A randomized, placebo-controlled, double-blind, crossover study in 40 lumbar spinal stenosis patients with a 1-year follow-up showed that calcitonin had beneficial effects on the patients' symptoms without producing any notable side effects. Calcitonin had a clear analgesic effect. The mean of walking distance increased, but the crossover trend was not as good as the analgesic effect. Side effects such as erythema and nausea were usually mild and transient. Calcitonin therapy can be used as a conservative treatment in selected cases of lumbar spinal stenosis. When rest pain was mild or the walking distance was under 200-300 m because of neurogenic claudication, the effect of calcitonin seemed to be poor.

摘要

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本文引用的文献

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Subarachnoid injection of salmon calcitonin induces analgesia in man.蛛网膜下腔注射鲑鱼降钙素可在人体中诱导镇痛作用。
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