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急性憩室炎住院治疗并不要求常规进行择期结肠切除术。

Hospitalization for acute diverticulitis does not mandate routine elective colectomy.

作者信息

Broderick-Villa Gregory, Burchette Raoul J, Collins J Craig, Abbas Maher A, Haigh Philip I

机构信息

Department of Surgery, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA 90027, USA.

出版信息

Arch Surg. 2005 Jun;140(6):576-81; discussion 581-3. doi: 10.1001/archsurg.140.6.576.

Abstract

BACKGROUND

Previous studies suggest that elective colectomy is often required after an episode of acute diverticulitis.

HYPOTHESIS

Acute diverticulitis initially treated nonoperatively does not require elective colectomy.

DESIGN

Retrospective cohort study.

SETTING

Twelve Kaiser Permanente hospitals in Southern California.

PATIENTS

Three thousand one hundred sixty-five patients with acute diverticulitis.

INTERVENTIONS

Colectomy or nonoperative treatment with or without percutaneous abscess drainage.

MAIN OUTCOME MEASURES

Recurrent diverticulitis.

RESULTS

Emergency colectomy was performed in 614 patients (19.4%). Nonoperative treatment was initially used in 2551 patients (80.6%). Of these, 185 patients (7.3%) had an elective colectomy and the remaining 2366 patients (92.7%) did not. Factors associated with undergoing elective colectomy compared with nonoperative treatment were younger age of the patient, fewer comorbidities, and percutaneous abscess drainage. Mean follow-up was 8.9 years, with a maximum of 12 years. After nonoperative treatment, 314 patients (13.3%) recurred-222 patients had a single recurrence and 92 patients had a rerecurrence. After adjusting for other variables, older age (hazard ratio, >/=50 years vs <50 years = 0.68; 95% confidence interval, 0.53-0.87) was associated with a lower recurrence, whereas higher comorbidity was associated with higher recurrence. Gender and percutaneous abscess drainage had no influence on recurrence. All 92 rerecurrences were treated nonoperatively. The risk of a rerecurrence (29.3%) was significantly higher than a first recurrence (P<.001). Age, gender, Charlson comorbidity index, and percutaneous abscess drainage did not predict rerecurrence.

CONCLUSIONS

Very few patients with acute diverticulitis treated nonoperatively have recurrence. Younger age was associated with recurrence. A first recurrence was the only factor that predicted rerecurrences. The low recurrence rate argues against routine elective colectomy after successful nonoperative management of acute diverticulitis.

摘要

背景

既往研究表明,急性憩室炎发作后常需行择期结肠切除术。

假设

初始采用非手术治疗的急性憩室炎无需行择期结肠切除术。

设计

回顾性队列研究。

地点

南加州的12家凯撒医疗机构医院。

患者

3165例急性憩室炎患者。

干预措施

结肠切除术或采用或不采用经皮脓肿引流的非手术治疗。

主要观察指标

复发性憩室炎。

结果

614例患者(19.4%)接受了急诊结肠切除术。2551例患者(80.6%)初始采用非手术治疗。其中,185例患者(7.3%)接受了择期结肠切除术,其余2366例患者(92.7%)未接受。与非手术治疗相比,接受择期结肠切除术的相关因素包括患者年龄较轻、合并症较少以及经皮脓肿引流。平均随访8.9年,最长12年。非手术治疗后,314例患者(13.3%)复发——222例患者单次复发,92例患者再次复发。在对其他变量进行校正后,年龄较大(风险比,≥50岁与<50岁相比=0.68;95%置信区间,0.53 - 0.87)与较低的复发率相关,而合并症较多与较高的复发率相关。性别和经皮脓肿引流对复发无影响。所有92例再次复发患者均采用非手术治疗。再次复发的风险(29.3%)显著高于首次复发(P<0.001)。年龄、性别、查尔森合并症指数和经皮脓肿引流均不能预测再次复发。

结论

非手术治疗的急性憩室炎患者很少复发。年龄较轻与复发相关。首次复发是预测再次复发的唯一因素。低复发率表明在急性憩室炎非手术治疗成功后,反对常规行择期结肠切除术。

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