Ambrosetti P, Robert J H, Witzig J A, Mirescu D, Mathey P, Borst F, Rohner A
Department of Digestive Surgery, University Hospital, Geneva, Switzerland.
J Am Coll Surg. 1994 Aug;179(2):156-60.
This prospective study was done to compare acute left-sided colonic diverticulitis in young patients (50 years of age or less) and older patients (more than 50 years of age) for severity of disease and immediate and late outcome.
Of the 265 patients studied, 61 were 50 years of age or less; of these, 49 were men. In all instances, diagnosis was confirmed radiologically or histologically.
Operations were performed less often upon younger patients than older patients (15 versus 33 percent, p = 0.001). Severe diverticulitis was found more often in younger men than older men (39 versus 23 percent). After successful conservative treatment during the first hospitalization period, younger men had a statistically greater risk of poor outcome than older men (29 versus 5 percent, p = 0.003).
Although younger men have severe acute diverticulitis more often than older men, operative treatment during the first episode is less often needed. On the other hand, after conservative treatment, younger men have a statistically greater chance of poor secondary outcome than older men.
本前瞻性研究旨在比较年轻患者（50岁及以下）和老年患者（50岁以上）急性左侧结肠憩室炎的疾病严重程度以及近期和远期预后。
在研究的265例患者中，61例年龄在50岁及以下；其中49例为男性。所有病例均经影像学或组织学确诊。
年轻患者接受手术治疗的频率低于老年患者（15%对33%，p = 0.001）。年轻男性中重度憩室炎的发生率高于老年男性（39%对23%）。在首次住院期间成功进行保守治疗后，年轻男性预后不良的统计学风险高于老年男性（29%对5%，p = 0.003）。
尽管年轻男性比老年男性更常发生严重急性憩室炎，但首次发作时较少需要手术治疗。另一方面，保守治疗后，年轻男性继发不良预后的统计学几率高于老年男性。
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