Wongkamchai Sirichit, Rongsriyam Kanisa, Nochot Hathai, Mahakittikun Vanna, Sermsart Bunguorn, Choochote Wej, Kanjanopart Kobkarn
Faculty of Medicine, Department of Parasitology, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Exp Appl Acarol. 2005;35(4):293-300. doi: 10.1007/s10493-004-7083-x.
The acaricidal activity of synthetic pyrethroid and benzyl benzoate against Dermatophagoides pteronyssinus was examined in the laboratory, using a specially designed test set up. On the basis of median lethal dose (LD50) values, the compound found to be most toxic to D. pteronyssinus was benzyl benzoate (LD50 = 50 mg/m2), followed by permethrin (LD50 = 76.7 mg/m2), deltamethrin (LD50 = 146.7 mg/m2), esbioallenthrin (LD50 = 186.6 mg/m2) and lamdacyhalothrin (LD50 = 756.6 mg/m2). Very low toxicity was observed with bifenthrin (LD50 = 5157.8 mg/m2). A laboratory control trial was also carried out to compare the acaricidal activity (residual effect) of four pyrethroids impregnated on woven and non-woven encasement materials against house dust mites during a 4-month period. Of the pyrethroids used in this study, esbioallenthrin demonstrated the highest acaricidal activity, and of the pyrethroid impregnated materials, the non-woven encasement material was more effective than the woven encasement material.
在实验室中，使用专门设计的测试装置，检测了合成拟除虫菊酯和苯甲酸苄酯对尘螨的杀螨活性。根据半数致死剂量（LD50）值，发现对尘螨毒性最大的化合物是苯甲酸苄酯（LD50 = 50毫克/平方米），其次是氯菊酯（LD50 = 76.7毫克/平方米）、溴氰菊酯（LD50 = 146.7毫克/平方米）、乙氰菊酯（LD50 = 186.6毫克/平方米）和高效氯氟氰菊酯（LD50 = 756.6毫克/平方米）。联苯菊酯的毒性非常低（LD50 = 5157.8毫克/平方米）。还进行了一项实验室对照试验，以比较四种浸渍在机织和非织造包裹材料上的拟除虫菊酯在4个月期间对屋尘螨的杀螨活性（残留效果）。在本研究中使用的拟除虫菊酯中，乙氰菊酯表现出最高的杀螨活性，在浸渍了拟除虫菊酯的材料中，非织造包裹材料比机织包裹材料更有效。
