Raynaud S, Fourneau C, Laurens A, Hocquemiller R, Loiseau P, Bories C
Planta Med. 2000 Mar;66(2):173-5. doi: 10.1055/s-0029-1243125.
Annonaceae have been commonly described in traditional medicine as remedies against head lice and for their insecticidal properties. Acaricidal effects of Uvaria pauci-ovulata bark extracts were investigated on Dermatophagoides pteronyssinus, the European house dust mite, and compared with those of benzyl benzoate used as standard acaricidal compound. A dichloromethane extract was the most effective with an EC50 = 0.028 g/m2 after a 24 h period as compared with benzyl benzoate (EC50 = 0.06 g/m2). Bioassay-guided fractionation of this extract led to the isolation of benzyl benzoate and squamocin; this latter compound also had acaricidal properties (EC50 = 0.6 g/m2). Moreover, squamocin was shown to potentiate the activity of benzyl benzoate using the fractional effective concentration (FEC) method.
番荔枝科植物在传统医学中通常被描述为治疗头虱的药物，并因其具有杀虫特性。研究了少子紫玉盘树皮提取物对欧洲屋尘螨——粉尘螨的杀螨效果，并与用作标准杀螨化合物的苯甲酸苄酯进行了比较。二氯甲烷提取物最为有效，在24小时后其半数有效浓度（EC50）=0.028克/平方米，而苯甲酸苄酯的EC50=0.06克/平方米。对该提取物进行生物测定导向的分级分离，得到了苯甲酸苄酯和鳞木素；后一种化合物也具有杀螨特性（EC50=0.6克/平方米）。此外，使用分数效应浓度（FEC）法表明鳞木素可增强苯甲酸苄酯的活性。
