Crit Care Med. 1992 Jun;20(6):864-74.
To define the terms "sepsis" and "organ failure" in a precise manner.
Review of the medical literature and the use of expert testimony at a consensus conference.
American College of Chest Physicians (ACCP) headquarters in Northbrook, IL.
Leadership members of ACCP/Society of Critical Care Medicine (SCCM).
An ACCP/SCCM Consensus Conference was held in August of 1991 with the goal of agreeing on a set of definitions that could be applied to patients with sepsis and its sequelae. New definitions were offered for some terms, while others were discarded. Broad definitions of sepsis and the systemic inflammatory response syndrome were proposed, along with detailed physiologic variables by which a patient could be categorized. Definitions for severe sepsis, septic shock, hypotension, and multiple organ dysfunction syndrome were also offered. The use of severity scoring methods were recommended when dealing with septic patients as an adjunctive tool to assess mortality. Appropriate methods and applications for the use and testing of new therapies were recommended.
The use of these terms and techniques should assist clinicians and researchers who deal with sepsis and its sequelae.
以精确的方式定义“脓毒症”和“器官衰竭”这两个术语。
对医学文献的回顾以及在一次共识会议上使用专家证词。
伊利诺伊州诺斯布鲁克的美国胸科医师学会（ACCP）总部。
ACCP/危重病医学会（SCCM）的领导成员。
1991年8月召开了一次ACCP/SCCM共识会议，目的是就一套可应用于脓毒症患者及其后遗症的定义达成一致。为一些术语提供了新定义，而其他一些则被摒弃。提出了脓毒症和全身炎症反应综合征的宽泛定义，以及可据此对患者进行分类的详细生理变量。还给出了严重脓毒症、脓毒性休克、低血压和多器官功能障碍综合征的定义。建议在处理脓毒症患者时使用严重程度评分方法作为评估死亡率的辅助工具。推荐了使用和测试新疗法的适当方法及应用。
这些术语和技术的使用应有助于处理脓毒症及其后遗症的临床医生和研究人员。
