Campbell A P
Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, Headington, Oxford.
J Clin Pathol. 1992 May;45(5):443-4. doi: 10.1136/jcp.45.5.443.
Bizzare multinucleated stromal giant cells were observed in a case of adolescent gynaecomastia. Similar cells have been described in the female breast in both benign and malignant conditions where they are thought to originate either from reactive stromal cells or from the mononuclear phagocyte system, respectively. Immunohistochemistry and electron microscopy in this case support the idea that they originate from stromal fibroblasts. Their occurrence in gynaecomastia is further evidence that these changes in stromal cells may be due to hormonal influences.
在一例青春期男性乳腺增生症中观察到奇异的多核间质巨细胞。在女性乳腺的良性和恶性病变中均有类似细胞的描述，在这些病变中，它们分别被认为起源于反应性间质细胞或单核吞噬细胞系统。该病例的免疫组织化学和电子显微镜检查支持它们起源于间质成纤维细胞的观点。它们在男性乳腺增生症中的出现进一步证明，间质细胞的这些变化可能是由激素影响所致。
