Hassan M O, Olaizola M Y
Arch Pathol Lab Med. 1979 Nov;103(12):624-30.
Ten cases of gynecomastia were studied by electron microscopy. The ducts showed proliferation of both epithelial and myoepithelial cells. Intracytoplasmic lumina, previously thought to be a feature of malignant breast lesions, were seen. Squamous metaplasia was observed in some cases. The stroma showed fibroblasts, myofibroblasts, and, occasionally, pericytes. The general morphology of gynecomastia is similar to that of benign lesions of the female breast at the ultrastructural level. The features of the stromal cells reflect the effects of estrogenic stimulation.
对10例男性乳腺增生症进行了电子显微镜研究。导管显示上皮细胞和肌上皮细胞均增生。可见胞质内管腔，以前认为这是乳腺恶性病变的一个特征。在某些病例中观察到鳞状化生。间质可见成纤维细胞、肌成纤维细胞，偶尔还有周细胞。在超微结构水平上，男性乳腺增生症的总体形态与女性乳腺良性病变相似。间质细胞的特征反映了雌激素刺激的作用。
