Abdul-Karim F W, Cohen R E
Institute of Pathology, Case Western Reserve University, University Hospitals of Cleveland, Ohio.
Histopathology. 1990 Sep;17(3):249-53. doi: 10.1111/j.1365-2559.1990.tb00715.x.
Atypical stromal cells were identified in either the cervix or vagina in 27 (13%) of 205 autopsy specimens. They were more commonly observed in the vulva, occurring in 29 (78.4%) of 37 vulvar surgical specimens. In only seven patients were the cells present as a continuous band; five in cervix or vagina and two in vulva. Electronmicroscopic examination confirmed the fibroblastic nature of these cells. Although hormonal influences may be responsible for this stromal alteration, their occurrence in elderly patients and in males at other sites is not consistent with a specific hormonal profile. It is important not to misdiagnose these cells as malignant.
在205份尸检标本中，有27份（13%）在宫颈或阴道中发现了非典型间质细胞。它们在外阴中更常见，在37份外阴手术标本中有29份（78.4%）出现。只有7例患者的细胞呈连续带状分布；5例在宫颈或阴道，2例在外阴。电子显微镜检查证实了这些细胞的成纤维细胞性质。虽然激素影响可能是这种间质改变的原因，但它们在老年患者和其他部位的男性中出现与特定的激素谱不一致。重要的是不要将这些细胞误诊为恶性。
