Zai-Chang Yang, Bo-Chu Wang, Xiao-Sheng Yang, Qiang Wang
Key Laboratory of Biomechanics & Tissue Engineering (Chongqing University), Ministry of Education Bioengineering College of Chongqing University, Chongqing 400044, PR China.
Colloids Surf B Biointerfaces. 2005 Jul 10;43(3-4):198-202. doi: 10.1016/j.colsurfb.2005.05.003.
The volatile oil of the roots of Cynanchum stauntonii was examined by gas chromatography-mass spectrometry (GC-MS). Thirty-eight constituents were identified. (E,E)-2,4-Decadienal, 3-efhyl-4-methypentanol, 5-pentyl-3H-furan-2-one, (E,Z)-2,4-decadienal and 2(3H)-furanone,dihydro-5-pentyl were found to be the major components. The volatile oil exhibited the activities against influenza virus in vitro (IC50s=64 microg/ml). In in vivo experiment, it prevented influenza virus-induced deaths in a dose-dependent manner.
采用气相色谱-质谱联用（GC-MS）法对白薇根的挥发油进行了检测。鉴定出38种成分。发现（E,E）-2,4-癸二烯醛、3-乙基-4-甲基戊醇、5-戊基-3H-呋喃-2-酮、（E,Z）-2,4-癸二烯醛和二氢-5-戊基-2（3H）-呋喃酮为主要成分。该挥发油在体外表现出抗流感病毒活性（IC50=64μg/ml）。在体内实验中，它以剂量依赖的方式预防流感病毒诱导的死亡。
